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How to get fromMyrtle Beach to Key West (Island)by plane, bus, train, bus (Greyhound, Flixbus), or car

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There are 4 ways to get from Myrtle Beach to Key West (Island) by plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Myrtle Beach (MYR) to Key West International Airport (EYW)plane plane MYR - EYW
    4h 34m
    $72–324

  2. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    2. Take the train from Charleston Amtrak Station to Hollywood Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Key West Airportbus bus
    23h 27m
    $399–627

  3. Bus

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the bus from Fayetteville Bus Station to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Key West Airportbus bus
    25h 5m
    $176–276

  4. Drive  834.4 mi

    1. Drive from Myrtle Beach to Key Westcar car 834.4 mi
    15h 21m
    $143–206

Myrtle Beach to Key West (Island) by bus and train

Calendar7Weekly Services
Duration23h 27mAverage Duration
Ticket$399Cheapest Price
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Comparing Your Travel Options

Map of how to get from Myrtle Beach to Key West (Island).ExpandLaunch map view
  • Distance: 656.2 mi
  • Duration: 4h 34m

What companies run services between Myrtle Beach, SC, USA and Key West (Island), FL, USA?

American Airlines and Delta fly from Myrtle Beach (MYR) to Key West International Airport (EYW) 5 times a day. Alternatively, you can take a bus from Myrtle Beach Bus Station to Key West Airport via Fayetteville Bus Station and Miami Airport Station in around 25h 5m.

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Want to know more about travelling around United States

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