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How to get fromMyrtle Beach to Lancasterby plane, bus, bus (Greyhound, Flixbus), train, or car

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There are 7 ways to get from Myrtle Beach to Lancaster by plane, bus, bus (Greyhound, Flixbus), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Harrisburg International Airport, line 18 bus

    best
    1. Fly from Myrtle Beach (MYR) to Harrisburg International Airport (MDT)plane plane MYR - MDT
    2. Take the bus from AMTRAK ETown to W. Chestnut & Water St.bus bus
    5h 44m

  2. Bus via Wilmington

    cheapest
    1. Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus bus
    2. Take the bus from Wilmington Cape Fear Public Transit to Raleigh Bus Stationbus bus
    3. Take the bus from Raleigh Bus Station to Washington Union Stationbus bus
    4. Take the bus from Washington Union Station to Harrisburg Bus Stationbus bus
    18h 32m
    $94–184

  3. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    2. Take the train from Charleston Amtrak Station to 30th Street Stationtrain train
    3. Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain train
    20h 23m
    $242–509

  4. Drive 521.5 mi

    1. Drive from Myrtle Beach to Lancastercar car 521.5 mi
    10h 10m
    $96–138

  5. Fly to Philadelphia International Airport, train, line 18 bus

    1. Fly from Myrtle Beach (MYR) to Philadelphia International Airport (PHL)plane plane MYR - PHL
    2. Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain train
    3. Take the bus from AMTRAK ETown to W. Chestnut & Water St.bus bus
    6h 58m

  6. Bus

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the bus from Fayetteville Bus Station to Baltimore Downtown Bus Stationbus bus
    3. Take the bus from Baltimore Downtown Bus Station to Harrisburg Bus Stationbus bus
    23h 42m
    $130–247

  7. Bus, train via Fayetteville

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the train from Fayetteville Amtrak Station to 30th Street Stationtrain train
    3. Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain train
    23h 50m
    $226–482

Myrtle Beach to Lancaster by bus and train

Calendar7Weekly Services
Duration18h 32mAverage Duration
Ticket$94Cheapest Price
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Questions & Answers

Map of how to get from Myrtle Beach to Lancaster.ExpandLaunch map view
  • Distance: 518.8 mi
  • Duration: 5h 44m

What companies run services between Myrtle Beach, SC, USA and Lancaster, PA, USA?

You can take a bus from Myrtle Beach Bus Station to W. Chestnut & Water St. via Wilmington Cape Fear Public Transit, Raleigh Bus Station, Washington Union Station, Harrisburg Bus Station, Harrisburg, Elizabethtown Amtrak Station, and AMTRAK ETown in around 18h 32m.

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