What is the cheapest way to get from Myrtle Beach to Louisville?

The cheapest way to get from Myrtle Beach to Louisville is to drive which costs $110 - $170 and takes 12h 30m.

What is the fastest way to get from Myrtle Beach to Louisville?

The fastest way to get from Myrtle Beach to Louisville is to fly which takes 4h 53m and costs $110 - $650.

Is there a direct bus between Myrtle Beach and Louisville?

No, there is no direct bus from Myrtle Beach station to Louisville. However, there are services departing from Myrtle Beach Bus Station and arriving at Louisville, KY via Atlanta Bus Station and Nashville. The journey, including transfers, takes approximately 18h 50m.

How far is it from Myrtle Beach to Louisville?

The distance between Myrtle Beach and Louisville is 504 miles. The road distance is 613.2 miles.

How do I travel from Myrtle Beach to Louisville without a car?

The best way to get from Myrtle Beach to Louisville without a car is to bus which takes 18h 50m and costs $120 - $210.

How long does it take to get from Myrtle Beach to Louisville?

It takes approximately 4h 53m to get from Myrtle Beach to Louisville, including transfers.

Where do I catch the Myrtle Beach to Louisville bus from?

Myrtle Beach to Louisville bus services, operated by Greyhound USA, depart from Myrtle Beach Bus Station.

Bus or fly from Myrtle Beach to Louisville?

The best way to get from Myrtle Beach to Louisville is to fly which takes 4h 53m and costs $110 - $650. Alternatively, you can bus, which costs $120 - $210 and takes 18h 50m.

Where does the Myrtle Beach to Louisville bus arrive?

Myrtle Beach to Louisville bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.

Can I drive from Myrtle Beach to Louisville?

Yes, the driving distance between Myrtle Beach to Louisville is 613 miles. It takes approximately 12h 30m to drive from Myrtle Beach to Louisville.

How do I get a bus ticket from Myrtle Beach to Louisville?

Book your Myrtle Beach to Louisville bus tickets online with Omio.

Where can I stay near Louisville?

There are 628+ hotels available in Louisville.

Myrtle Beach to Louisville - 5 ways to travel via plane, bus, and car

How to get fromMyrtle Beach to Louisville

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There are 5 ways to get from Myrtle Beach to Louisville by plane, bus (Greyhound, Flixbus, Amtrak), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly to Louisville International Airport
best
1. Fly from Myrtle Beach (MYR) to Louisville International Airport (SDF)plane MYR - SDF
4h 53m
$113–617
Fly to Blue Grass Airport, drive
cheapest
1. Fly from Myrtle Beach (MYR) to Blue Grass Airport (LEX)plane MYR - LEX
2. Drive from Lexington-Airport-LEX to Louisvillecar
4h 59m
$80–373
Bus
1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus
2. Take the bus from Atlanta Bus Station to Nashville Bus Stationbus
3. Take the bus from Nashville to Louisville, KYbus
18h 50m
$125–208
Drive 609.6 mi
1. Drive from Myrtle Beach to Louisvillecar 609.6 mi
12h 30m
$112–161
Bus via Preston @ Vim
1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus
2. Take the bus from Atlanta Bus Station to Nashville Bus Stationbus
3. Take the bus from Tornado Bus Co - Nashville to La Tropicana - Louisville, KYbus
19h 41m
$133–223

Myrtle Beach to Louisville by bus

7Weekly Buses

18h 50mAverage Duration

$125Cheapest Price

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Comparing Your Travel Options

Map of how to get from Myrtle Beach to Louisville.

Launch map view

Distance: 500.9 mi
Duration: 4h 53m

What companies run services between Myrtle Beach, SC, USA and Louisville, KY, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Myrtle Beach (MYR) to Louisville International Airport (SDF) hourly. Alternatively, you can take a bus from Myrtle Beach Bus Station to Louisville, KY via Atlanta Bus Station and Nashville in around 18h 50m.

Airlines

Bus operators

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