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How to get fromMyrtle Beach to Mechanicsburgby plane, bus (Greyhound, Flixbus), bus, train, or car

Find Transport to Mechanicsburg

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There are 7 ways to get from Myrtle Beach to Mechanicsburg by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Harrisburg International Airport

    best
    1. Fly from Myrtle Beach (MYR) to Harrisburg International Airport (MDT)plane plane MYR - MDT
    3h 26m
    $64–328

  2. Bus via Wilmington

    1. Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus bus
    2. Take the bus from Wilmington Cape Fear Public Transit to Raleigh Bus Stationbus bus
    3. Take the bus from Raleigh Bus Station to Baltimore Downtown Bus Stationbus bus
    4. Take the bus from Baltimore Downtown Bus Station to Harrisburg Bus Stationbus bus
    16h 14m
    $91–184

  3. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    2. Take the train from Charleston Amtrak Station to 30th Street Stationtrain train
    3. Take the train from 30th Street Station to Harrisburgtrain train
    19h 50m
    $247–522

  4. Drive 518.7 mi

    1. Drive from Myrtle Beach to Mechanicsburgcar car 518.7 mi
    9h 50m
    $95–137

  5. Fly to Hagerstown Regional Airport, drive

    1. Fly from Myrtle Beach (MYR) to Hagerstown Regional Airport (HGR)plane plane MYR - HGR
    2. Drive from Hagerstown-Airport-HGR to Mechanicsburgcar car
    2h 44m
    $72–330

  6. Bus

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the bus from Fayetteville Bus Station to Baltimore Downtown Bus Stationbus bus
    3. Take the bus from Baltimore Downtown Bus Station to Harrisburg Bus Stationbus bus
    21h 29m
    $129–242

  7. Bus, train via Fayetteville

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the train from Fayetteville Amtrak Station to Washington Union Stationtrain train
    3. Take the bus from Washington Union Station to Harrisburg Bus Stationbus bus
    21h 42m
    $180–373

Myrtle Beach to Mechanicsburg by bus and foot

Calendar14Weekly Services
Duration16h 14mAverage Duration
Ticket$91Cheapest Price
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Questions & Answers

Map of how to get from Myrtle Beach to Mechanicsburg.ExpandLaunch map view
  • Distance: 487.5 mi
  • Duration: 3h 26m

What companies run services between Myrtle Beach, SC, USA and Mechanicsburg, Cumberland County, PA, USA?

Allegiant Air, United Airlines, and American Airlines fly from Myrtle Beach (MYR) to Harrisburg International Airport (MDT) twice daily. Alternatively, you can take a bus from Myrtle Beach Bus Station to E Main St & Arch St WB via Wilmington Cape Fear Public Transit, Raleigh Bus Station, Baltimore Downtown Bus Station, Harrisburg Bus Station, and Market Square Transfer Center in around 16h 14m.

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