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How to get fromMyrtle Beach to Mechanicsburgby plane, bus (Greyhound, Flixbus), bus, train, or car

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There are 5 ways to get from Myrtle Beach to Mechanicsburg by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Myrtle Beach (MYR) to Harrisburg International Airport (MDT)plane plane MYR - MDT
    3h 28m
    $69–348

  2. Bus

    1. Take the bus from Myrtle Beach Bus Station to Raleigh Bus Stationbus bus
    2. Take the bus from Raleigh Bus Station to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Harrisburg Bus Stationbus bus
    14h 54m
    $101–160

  3. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the train from Fayetteville Amtrak Station to Washington Union Stationtrain train
    3. Take the bus from Washington Union Station to Harrisburg Bus Stationbus bus
    15h 32m
    $219–353

  4. Drive  518.7 mi

    1. Drive from Myrtle Beach to Mechanicsburgcar car 518.7 mi
    9h 51m
    $89–129

  5. Bus via Fayetteville

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the bus from Fayetteville Bus Station to Baltimore Downtown Bus Stationbus bus
    3. Take the bus from Baltimore Downtown Bus Station to Harrisburg Bus Stationbus bus
    18h 34m
    $111–173

Myrtle Beach to Mechanicsburg by bus and foot

Calendar4Weekly Services
Duration14h 54mAverage Duration
Ticket$101Cheapest Price
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Comparing Your Travel Options

Map of how to get from Myrtle Beach to Mechanicsburg.ExpandLaunch map view
  • Distance: 487.5 mi
  • Duration: 3h 28m

What companies run services between Myrtle Beach, SC, USA and Mechanicsburg, Cumberland County, PA, USA?

Allegiant Air and American Airlines fly from Myrtle Beach (MYR) to Harrisburg International Airport (MDT) 4 times a day. Alternatively, you can take a bus from Myrtle Beach Bus Station to E Main St & Arch St WB via Raleigh Bus Station, Washington Union Station, Harrisburg Bus Station, and Market Square Transfer Center in around 14h 54m.

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Need to know: Greyhound

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