Rome2Rio

How to get fromMyrtle Beach to Mesaby plane, bus (Greyhound), bus, train, or car

Find Transport to Mesa

See all options

There are 6 ways to get from Myrtle Beach to Mesa by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Myrtle Beach

    best
    1. Fly from Myrtle Beach (MYR) to Phoenix (PHX)plane plane MYR - PHX
    7h 36m
    $144–616

  2. Bus (Greyhound)

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Phoenix Bus Stationbus bus
    2d 3h
    $362–575

  3. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the train from Fayetteville Amtrak Station to Petersburg Amtrak Stationtrain train
    3. Take the train from Petersburg Amtrak Station to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Flagstafftrain train
    5. Take the bus from Flagstaff Train Station to Phoenix Sky Harbor Airport/44th Street Sky Train Stationbus bus
    2d 18h
    $1,549–2,536

  4. Drive  2,137.1 mi

    1. Drive from Myrtle Beach to Mesacar car 2,137.1 mi
    35h 3m
    $390–564

  5. Bus to Florence Regional Airport, fly

    1. Take the bus from Myrtle Beach Bus Station to Florence Bus Stationbus bus
    2. Fly from Florence Regional Airport (FLO) to Phoenix (PHX)plane plane FLO - PHX
    10h 32m
    $155–634

  6. Bus, train via New Orleans

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the bus from Fayetteville to High Pointbus bus
    3. Take the train from High Point to New Orleans Union Passenger Terminaltrain train
    4. Take the train from New Orleans Union Passenger Terminal to Tucson Amtrak Stationtrain train
    5. Take the bus from Tucson Downtown to Tempebus bus
    2d 21h
    $1,331–2,144

Myrtle Beach to Mesa by bus and tram (Greyhound)

Calendar7Weekly Services
Duration2d 3hAverage Duration
Ticket$362Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Myrtle Beach to Mesa.ExpandLaunch map view
  • Distance: 1,911.7 mi
  • Duration: 7h 36m

What companies run services between Myrtle Beach, SC, USA and Mesa, AZ, USA?

Delta, Southwest Airlines, and American Airlines fly from Myrtle Beach (MYR) to Phoenix (PHX) hourly. Alternatively, you can take a bus from Myrtle Beach Bus Station to Mesa Dr/Main St via Atlanta Bus Station, Dallas Bus Station, Phoenix, Bus Station (E Buckeye Rd), 24th St Station, Phoenix Sky Harbor Airport/44th Street Sky Train Station, and 44th St/Washington in around 2d 3h.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There