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How to get fromMyrtle Beach to Millsboroby plane, bus, train, bus (Greyhound), car, or bus (Greyhound, Flixbus)

Find Transport to Millsboro

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There are 6 ways to get from Myrtle Beach to Millsboro by plane, bus, train, bus (Greyhound), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Myrtle Beach (MYR) to Salisbury–Ocean City–Wicomico Regional Airport (SBY)plane plane MYR - SBY
    5h 21m
    $152–474

  2. Drive  450.8 mi

    cheapest
    1. Drive from Myrtle Beach to Millsborocar car 450.8 mi
    9h 28m
    $83–119

  3. Bus, train via Fayetteville

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the train from Fayetteville Amtrak Station to Wilmingtontrain train
    3. Take the bus from Wilmington Tc to Rehoboth P-N-R @ Country Club Rdbus bus 305
    17h 18m
    $262–419

  4. Bus

    1. Take the bus from Myrtle Beach Bus Station to Norfolkbus bus
    2. Take the bus from Norfolk, VA - Best Square to Dover Downs Hotel & Casinobus bus
    3. Take the bus from Dover Transit Center to Lewes Transit Centerbus bus 307
    17h 51m
    $115–163

  5. Bus via Raleigh

    1. Take the bus from Myrtle Beach Bus Station to Raleigh Bus Stationbus bus
    2. Take the bus from Raleigh Bus Station to Baltimore Downtown Bus Stationbus bus
    3. Take the bus from Baltimore Downtown Bus Station to Wilmington Bus Stationbus bus
    4. Take the bus from Wilmington Tc to Rehoboth P-N-R @ Country Club Rdbus bus 305
    18h 15m
    $94–159

  6. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    2. Take the train from Charleston Amtrak Station to Wilmingtontrain train
    3. Take the bus from Wilmington Tc to Rehoboth P-N-R @ Country Club Rdbus bus 305
    20h 1m
    $353–585

Myrtle Beach to Millsboro by bus and train

Calendar7Weekly Services
Duration17h 18mAverage Duration
Ticket$262Cheapest Price
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Comparing Your Travel Options

Map of how to get from Myrtle Beach to Millsboro.ExpandLaunch map view
  • Distance: 401.5 mi
  • Duration: 5h 21m

What companies run services between Myrtle Beach, SC, USA and Millsboro, DE, USA?

American Airlines and Breeze Airways fly from Myrtle Beach (MYR) to Salisbury–Ocean City–Wicomico Regional Airport (SBY) 5 times a day. Alternatively, you can take a bus from Myrtle Beach Bus Station to Monroe St At Brandywine Village Apts via Norfolk, VA - Best Square, Dover Downs Hotel & Casino, Delaware State University, Dover Transit Center, Lewes Transit Center, and Rehoboth P-N-R @ Country Club Rd in around 17h 51m.

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