There are 6 ways to get from Myrtle Beach to Mississippi by plane, bus (Greyhound), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Gulfport-Biloxi Regional Airport
best- Fly from Myrtle Beach (MYR) to Gulfport-Biloxi Regional Airport (GPT)plane MYR - GPT
4h 16m$83–378Bus (Greyhound)
- Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus Greyhound US0641S
- Take the bus from Atlanta Bus Station to Jacksonbus Greyhound US0604
17h 35m$138–210Drive 730.2 mi
- Drive from Myrtle Beach to Jacksoncar 730.2 mi
12h 42m$125–181Fly to Memphis
- Fly from Myrtle Beach (MYR) to Memphis (MEM)plane MYR - MEM
4h$154–741Fly to Jackson/Vicksburg
- Fly from Myrtle Beach (MYR) to Jackson/Vicksburg (JAN)plane MYR - JAN
4h 39m$112–414Fly to Mobile Regional Airport, bus
- Fly from Myrtle Beach (MYR) to Mobile Regional Airport (MOB)plane MYR - MOB
- Take the bus from Mobile Bus Station to Biloxi Transit Centerbus
6h 37m$105–399
Myrtle Beach to Mississippi by bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Myrtle Beach to Mississippi is to drive which costs $120 - $180 and takes 12h 42m.
The fastest way to get from Myrtle Beach to Mississippi is to fly which takes 4h and costs $150 - $750.
No, there is no direct bus from Myrtle Beach station to Mississippi. However, there are services departing from Myrtle Beach Bus Station and arriving at Jackson via Atlanta Bus Station. The journey, including transfers, takes approximately 17h 35m.
The distance between Myrtle Beach and Mississippi is 645 miles. The road distance is 734.5 miles.
The best way to get from Myrtle Beach to Mississippi without a car is to bus which takes 17h 35m and costs $130 - $210.
It takes approximately 4h 16m to get from Myrtle Beach to Mississippi, including transfers.
Myrtle Beach to Mississippi bus services, operated by Greyhound USA, depart from Myrtle Beach Bus Station.
The best way to get from Myrtle Beach to Mississippi is to fly which takes 4h 16m and costs $80 - $380. Alternatively, you can bus, which costs $130 - $210 and takes 17h 35m.
Myrtle Beach to Mississippi bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Mississippi is 1h behind Myrtle Beach. It is currently 10:52 AM in Myrtle Beach and 9:52 AM in Mississippi.
What companies run services between Myrtle Beach, SC, USA and Mississippi, USA?
Delta, American Airlines, and Breeze Airways fly from Myrtle Beach (MYR) to Gulfport-Biloxi Regional Airport (GPT) 4 times a day. Alternatively, you can take a bus from Myrtle Beach Bus Station to Jackson via Atlanta Bus Station in around 17h 35m.
- Website
- aa.com
Flights from Myrtle Beach to Gulfport-Biloxi Regional Airport via Charlotte
- Ave. Duration
- 5h 3m
- When
- Monday, Tuesday, Wednesday, and Saturday
- Estimated price
- $65–360
Flights from Myrtle Beach to Memphis via Charlotte
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $120–700
Flights from Myrtle Beach to Jackson/Vicksburg via Charlotte
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $65–360
Flights from Myrtle Beach to Mobile Regional Airport via Charlotte
- Ave. Duration
- 5h 6m
- When
- Every day
- Estimated price
- $65–350
Flights from Myrtle Beach to Mobile Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 9h 12m
- When
- Every day
- Estimated price
- $110–490
- Website
- delta.com
Flights from Myrtle Beach to Gulfport-Biloxi Regional Airport via Atlanta
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $60–350
Flights from Myrtle Beach to Memphis via Atlanta
- Ave. Duration
- 4h 3m
- When
- Monday, Tuesday, Wednesday, Thursday, Sunday, and Saturday
- Estimated price
- $120–700
Flights from Myrtle Beach to Jackson/Vicksburg via Atlanta
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $60–350
Flights from Myrtle Beach to Mobile Regional Airport via Atlanta
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $60–340
- Website
- southwest.com
Flights from Myrtle Beach to Memphis via Nashville
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $120–700
Flights from Myrtle Beach to Jackson/Vicksburg via Nashville
- Ave. Duration
- 8h
- When
- Tuesday and Wednesday
- Estimated price
- $70–370
- Website
- flybreeze.com
Flights from Myrtle Beach to Gulfport-Biloxi Regional Airport via Orlando
- Ave. Duration
- 5h 19m
- When
- Thursday and Sunday
- Estimated price
- $140–800
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Myrtle Beach Bus Station to Atlanta Bus Station
- Ave. Duration
- 8h 55m
- Frequency
- Twice daily
- Estimated price
- $65–100
- Website
- Greyhound
Bus from Atlanta Bus Station to Jackson
- Ave. Duration
- 7h 40m
- Frequency
- 4 times a day
- Estimated price
- $70–110
- Website
- Greyhound
Bus from Mobile Bus Station to Biloxi Transit Center
- Ave. Duration
- 1h 5m
- Frequency
- 4 times a day
- Estimated price
- $10–15
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Mobile Bus Station to Biloxi Transit Center
- Ave. Duration
- 55 min
- Frequency
- Twice daily
- Estimated price
- $8–13
- Schedules at
- Flixbus USA
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Booking & Getting There
Yes, the driving distance between Myrtle Beach to Mississippi is 734 miles. It takes approximately 12h 42m to drive from Myrtle Beach to Mississippi.
Book your Myrtle Beach to Mississippi bus tickets online with Omio and FlixBus.
There are 210+ hotels available in Mississippi.



