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How to get fromMyrtle Beach to Missouriby plane, bus (Greyhound, Flixbus), bus, train, or car

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There are 8 ways to get from Myrtle Beach to Missouri by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Lambert–St. Louis International Airport

    best
    1. Fly from Myrtle Beach (MYR) to Lambert–St. Louis International Airport (STL)plane plane MYR - STL
    2h 59m
    $105–507

  2. Fly to Springfield-Branson National Airport

    cheapest
    1. Fly from Myrtle Beach (MYR) to Springfield-Branson National Airport (SGF)plane plane MYR - SGF
    5h 4m
    $103–424

  3. Bus

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    25h 16m
    $191–317

  4. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Raleigh Bus Stationbus bus
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Kansas Citytrain train
    39h 22m
    $833–1,382

  5. Drive  1,127.6 mi

    1. Drive from Myrtle Beach to Kansas Citycar car 1,127.6 mi
    19h 41m
    $206–298

  6. Fly to Columbia Regional Airport

    1. Fly from Myrtle Beach (MYR) to Columbia Regional Airport (COU)plane plane MYR - COU
    5h 40m
    $132–459

  7. Fly to Kansas City

    1. Fly from Myrtle Beach (MYR) to Kansas City (MCI)plane plane MYR - MCI
    6h 7m
    $132–664

  8. Bus, train via Atlanta

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Kansas Citytrain train
    27h 8m
    $301–487

Myrtle Beach to Missouri by bus

Calendar7Weekly Buses
Duration25h 16mAverage Duration
Ticket$191Cheapest Price
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Comparing Your Travel Options

Map of how to get from Myrtle Beach to Missouri.ExpandLaunch map view
  • Distance: 743.3 mi
  • Duration: 2h 59m

What companies run services between Myrtle Beach, SC, USA and Missouri, USA?

Southwest Airlines, American Airlines, and Delta fly from Myrtle Beach (MYR) to Lambert–St. Louis International Airport (STL) 5 times a day. Alternatively, you can take a bus from Myrtle Beach Bus Station to Kansas City Bus Station via Atlanta Bus Station and St Louis Bus Station in around 25h 16m.

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