There are 10 ways to get from Myrtle Beach to Niagara Falls by plane, bus, bus (Greyhound, Flixbus), train, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Buffalo Niagara International Airport, bus
best- Fly from Myrtle Beach (MYR) to Buffalo Niagara International Airport (BUF)plane MYR - BUF
- Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus
5h 21m$117–622Fly to Toronto Island Airport, bus
cheapest- Fly from Myrtle Beach (MYR) to Toronto Island Airport (YTZ)plane MYR - YTZ
- Take the bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminalbus
7h 14m$80–410Bus
- Take the bus from Myrtle Beach Bus Station to Raleigh Bus Stationbus
- Take the bus from Raleigh Bus Station to Newark Penn Stationbus
- Take the bus from Newark Penn Station to Niagara Falls USAbus
24h$189–287Bus, train
- Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus
- Take the train from Fayetteville Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Niagara Falls Amtrak Stationtrain
25h 1m$577–910Drive 780.1 mi
- Drive from Myrtle Beach to Niagara Fallscar 780.1 mi
15h 55m$143–206Fly to Rochester, train
- Fly from Myrtle Beach (MYR) to Rochester (ROC)plane MYR - ROC
- Take the train from Rochester to Niagara Falls Amtrak Stationtrain
5h 28m$185–956Fly to Toronto Pearson International Airport, bus
- Fly from Myrtle Beach (MYR) to Toronto Pearson International Airport (YYZ)plane MYR - YYZ
- Take the bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminalbus
6h 58m$86–409Bus, train via Canadian Border
- Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus
- Take the train from Fayetteville Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Canadian Bordertrain
25h 29m$577–910Bus via Columbus
- Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus
- Take the bus from Fayetteville to Winston-Salembus
- Take the bus from Winston Salem to Columbusbus
- Take the bus from Columbus to Buffalobus
27h 28m$128–247Bus, train #2
- Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus
- Take the train from Charleston Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Niagara Falls Amtrak Stationtrain
27h 41m$668–1,076
Myrtle Beach to Niagara Falls by bus
Comparing Your Travel Options
The cheapest way to get from Myrtle Beach to Niagara Falls is to drive which costs $140 - $210 and takes 15h 55m.
The fastest way to get from Myrtle Beach to Niagara Falls is to fly and bus which takes 5h 21m and costs $110 - $650.
No, there is no direct bus from Myrtle Beach station to Niagara Falls. However, there are services departing from Myrtle Beach Bus Station and arriving at Niagara Falls USA via Raleigh Bus Station and Newark Penn Station. The journey, including transfers, takes approximately 24h.
The distance between Myrtle Beach and Niagara Falls is 677 miles. The road distance is 784.6 miles.
The best way to get from Myrtle Beach to Niagara Falls without a car is to bus which takes 24h and costs $180 - $290.
It takes approximately 5h 21m to get from Myrtle Beach to Niagara Falls, including transfers.
Myrtle Beach to Niagara Falls bus services, operated by Greyhound USA, depart from Myrtle Beach Bus Station.
Myrtle Beach to Niagara Falls bus services, operated by Greyhound USA, arrive at Raleigh Bus Station.
Yes, the driving distance between Myrtle Beach to Niagara Falls is 785 miles. It takes approximately 15h 55m to drive from Myrtle Beach to Niagara Falls.
Book your Myrtle Beach to Niagara Falls bus tickets online with Omio and FlixBus.
What companies run services between Myrtle Beach, SC, USA and Niagara Falls, NY, USA?
You can take a bus from Myrtle Beach Bus Station to Niagara Falls USA via Raleigh Bus Station and Newark Penn Station in around 24h.
- Website
- aa.com
Flights from Myrtle Beach to Buffalo Niagara International Airport via Charlotte
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $100–600
Flights from Myrtle Beach to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $110–600
Flights from Myrtle Beach to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $100–600
Flights from Myrtle Beach to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 7h 10m
- When
- Saturday
- Estimated price
- $120–650
Flights from Myrtle Beach to Rochester via Charlotte
- Ave. Duration
- 4h 11m
- When
- Monday, Thursday, Friday, Sunday, Wednesday, and Tuesday
- Estimated price
- $140–800
Flights from Myrtle Beach to Rochester via Reagan Washington
- Ave. Duration
- 4h 8m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–750
Flights from Myrtle Beach to Rochester via Philadelphia
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $140–800
Flights from Myrtle Beach to Toronto Pearson International Airport via Charlotte
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- $60–330
Flights from Myrtle Beach to Toronto Pearson International Airport via Reagan Washington
- Ave. Duration
- 4h 22m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $60–330
Flights from Myrtle Beach to Toronto Pearson International Airport via Philadelphia
- Ave. Duration
- 5h 51m
- When
- Every day
- Estimated price
- $65–340
Flights from Myrtle Beach to Toronto Pearson International Airport via New York La Guardia
- Ave. Duration
- 4h 44m
- When
- Saturday
- Estimated price
- $70–360
- Website
- southwest.com
Flights from Myrtle Beach to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $100–600
Flights from Myrtle Beach to Rochester via Baltimore
- Ave. Duration
- 3h 53m
- When
- Tuesday, Wednesday, Saturday, and Monday
- Estimated price
- $130–750
- Website
- delta.com
Flights from Myrtle Beach to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $120–650
Flights from Myrtle Beach to Buffalo Niagara International Airport via Atlanta
- Ave. Duration
- 5h 9m
- When
- Every day
- Estimated price
- $130–700
Flights from Myrtle Beach to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 6h 30m
- When
- Every day
- Estimated price
- $120–650
Flights from Myrtle Beach to Rochester via Detroit
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $160–850
Flights from Myrtle Beach to Toronto Pearson International Airport via New York La Guardia
- Ave. Duration
- 5h 14m
- When
- Every day
- Estimated price
- $70–360
Flights from Myrtle Beach to Toronto Pearson International Airport via Detroit
- Ave. Duration
- 6h 2m
- When
- Every day
- Estimated price
- $65–350
- Website
- flyporter.com
Flights from Myrtle Beach to Toronto Island Airport via Nashville
- Ave. Duration
- 5h 5m
- When
- Saturday
- Estimated price
- $180–750
Flights from Myrtle Beach to Toronto Island Airport via Boston
- Ave. Duration
- 5h 14m
- When
- Sunday
- Estimated price
- $85–410
Flights from Myrtle Beach to Toronto Island Airport via Newark
- Ave. Duration
- 8h 46m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $70–370
Flights from Myrtle Beach to Toronto Island Airport via Chicago O'Hare
- Ave. Duration
- 9h 3m
- When
- Every day
- Estimated price
- $85–410
Flights from Myrtle Beach to Toronto Island Airport via Washington Dulles
- Ave. Duration
- 9h 25m
- When
- Monday and Sunday
- Estimated price
- $60–340
Flights from Myrtle Beach to Toronto Island Airport via Charlotte, Washington Dulles
- Ave. Duration
- 6h 54m
- When
- Tuesday, Friday, and Sunday
- Estimated price
- $170–700
- Website
- united.com
Flights from Myrtle Beach to Toronto Island Airport via Washington Dulles
- Ave. Duration
- 8h 23m
- When
- Monday, Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- $60–340
Flights from Myrtle Beach to Toronto Island Airport via New York La Guardia
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $70–370
Flights from Myrtle Beach to Toronto Pearson International Airport via Washington Dulles
- Ave. Duration
- 8h 27m
- When
- Monday, Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- $60–330
- Website
- aircanada.com
Flights from Myrtle Beach to Toronto Island Airport via Washington Dulles
- Ave. Duration
- 8h 23m
- When
- Monday, Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- $60–340
Flights from Myrtle Beach to Toronto Island Airport via New York La Guardia
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $70–370
Flights from Myrtle Beach to Toronto Pearson International Airport via Washington Dulles
- Ave. Duration
- 8h 27m
- When
- Monday, Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- $60–330
- Website
- flybreeze.com
Flights from Myrtle Beach to Rochester
- Ave. Duration
- 2h 5m
- When
- Thursday and Sunday
- Estimated price
- $280–1,700
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Fayetteville Amtrak Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 10h 53m
- Frequency
- Twice daily
- Estimated price
- $300–470
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Niagara Falls Amtrak Station
- Ave. Duration
- 9h 8m
- Frequency
- 3 times a day
- Estimated price
- $250–400
- Website
- Amtrak
Train from Rochester to Niagara Falls Amtrak Station
- Ave. Duration
- 2h 7m
- Frequency
- 3 times a day
- Estimated price
- $50–80
- Website
- Amtrak
Train from Fayetteville Amtrak Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 10h 53m
- Frequency
- Twice daily
- Estimated price
- $300–470
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Canadian Border
- Ave. Duration
- 9h 36m
- Frequency
- Once daily
- Estimated price
- $250–400
- Website
- Amtrak
Train from Charleston Amtrak Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 14h 8m
- Frequency
- Twice daily
- Estimated price
- $400–650
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Niagara Falls Amtrak Station
- Ave. Duration
- 9h 8m
- Frequency
- 3 times a day
- Estimated price
- $250–400
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Rochester to Niagara Falls Amtrak Station
- Ave. Duration
- 2h 33m
- Frequency
- Once daily
- Estimated price
- $25–170
- Website
- VIA Rail
- Escape
- $25–80
- Business
- $55–160
- Business Plus
- $65–170
- Economy
- $28–85
- Economy Plus
- $30–95
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Buffalo Niagara International Airport to Niagara Falls USA
- Ave. Duration
- 50 min
- Frequency
- Every 4 hours
- Estimated price
- $5–8
- Schedules at
- Flixbus USA
Bus from Newark Penn Station to Niagara Falls USA
- Ave. Duration
- 8h 30m
- Frequency
- 4 times a day
- Estimated price
- $65–100
- Schedules at
- Flixbus USA
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Myrtle Beach Bus Station to Raleigh Bus Station
- Ave. Duration
- 4h 20m
- Frequency
- Once daily
- Estimated price
- $35–60
- Website
- Greyhound
Bus from Raleigh Bus Station to Newark Penn Station
- Ave. Duration
- 9h 10m
- Frequency
- 3 times a day
- Estimated price
- $85–130
- Website
- Greyhound
Bus from Myrtle Beach Bus Station to Fayetteville Bus Station
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $27–45
- Website
- Greyhound
Bus from Myrtle Beach Bus Station to Fayetteville Bus Station
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $27–45
- Website
- Greyhound
Bus from Myrtle Beach Bus Station to Fayetteville Bus Station
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $27–45
- Website
- Greyhound
Bus from Myrtle Beach Bus Station to Charleston Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $17–26
- Website
- Greyhound
- Phone
- +1 866 488 4452
- [email protected]
- Website
- Megabus
Bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminal
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- $7–55
- Website
- Megabus
- Adult Advanced Booking
- $7–45
- Adult Standard
- $16–55
Bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminal
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- $7–55
- Website
- Megabus
- Adult Advanced Booking
- $7–45
- Adult Standard
- $16–55
- Phone
- +1 704-348-1200
- [email protected]
- Website
- Sunway Charters
Bus from Fayetteville to Winston-Salem
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $24–35
- Schedules at
- Sunway Charters
- Passenger
- $24–35
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Winston Salem to Columbus
- Ave. Duration
- 9h 20m
- Frequency
- Once daily
- Estimated price
- $40–90
- Website
- Barons Bus
Bus from Columbus to Buffalo
- Ave. Duration
- 7h 15m
- Frequency
- Once daily
- Estimated price
- $35–80
- Website
- Barons Bus
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