There are 8 ways to get from Myrtle Beach to Niagara Falls by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Buffalo Niagara International Airport
best- Fly from Myrtle Beach (MYR) to Buffalo Niagara International Airport (BUF)plane MYR - BUF
6h 20m$109–544Fly to Toronto Pearson International Airport, bus
cheapest- Fly from Myrtle Beach (MYR) to Toronto Pearson International Airport (YYZ)plane MYR - YYZ
- Take the bus from Toronto Union Station to Niagara Falls, ONbus
7h 41m$85–398Bus
- Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus
- Take the bus from Wilmington Cape Fear Public Transit to Raleigh Bus Stationbus
- Take the bus from Raleigh Bus Station to Newark Penn Stationbus
- Take the bus from Newark Penn Station to Niagara Falls USAbus
25h 15m$150–290Bus, train
- Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus
- Take the train from Charleston Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Niagara Falls Amtrak Stationtrain
27h 36m$334–746Drive 780.1 mi
- Drive from Myrtle Beach to Niagara Fallscar 780.1 mi
15h 55m$143–206Fly to Rochester, train
- Fly from Myrtle Beach (MYR) to Rochester (ROC)plane MYR - ROC
- Take the train from Rochester to Niagara Falls Amtrak Stationtrain
5h 28m$235–906Bus, train via Fayetteville
- Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus
- Take the train from Fayetteville Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Canadian Bordertrain
31h 29m$325–723Bus via Columbus
- Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus
- Take the bus from Fayetteville to Winston-Salembus
- Take the bus from Winston Salem(Trans Center) to Columbus - Mound Stbus
- Take the bus from Columbus - Mound St to Buffalo, NYbus
33h 28m$148–315
Myrtle Beach to Niagara Falls by bus
Questions & Answers
The cheapest way to get from Myrtle Beach to Niagara Falls is to drive which costs $140 - $210 and takes 15h 55m.
The fastest way to get from Myrtle Beach to Niagara Falls is to fly and train which takes 5h 28m and costs $230 - $950.
No, there is no direct bus from Myrtle Beach station to Niagara Falls. However, there are services departing from Myrtle Beach Bus Station and arriving at Niagara Falls USA via Wilmington Cape Fear Public Transit, Raleigh Bus Station and Newark Penn Station. The journey, including transfers, takes approximately 25h 15m.
The distance between Myrtle Beach and Niagara Falls is 681 miles. The road distance is 784.6 miles.
The best way to get from Myrtle Beach to Niagara Falls without a car is to bus which takes 25h 15m and costs $150 - $290.
It takes approximately 6h 20m to get from Myrtle Beach to Niagara Falls, including transfers.
Myrtle Beach to Niagara Falls bus services, operated by Greyhound USA, depart from Myrtle Beach Bus Station.
The best way to get from Myrtle Beach to Niagara Falls is to fly which takes 6h 20m and costs $100 - $550. Alternatively, you can bus, which costs $150 - $290 and takes 25h 15m.
Myrtle Beach to Niagara Falls bus services, operated by Greyhound USA, arrive at Wilmington Cape Fear Public Transit station.
Yes, the driving distance between Myrtle Beach to Niagara Falls is 785 miles. It takes approximately 15h 55m to drive from Myrtle Beach to Niagara Falls.
What companies run services between Myrtle Beach, SC, USA and Niagara Falls, NY, USA?
Southwest Airlines, American Airlines, and Delta fly from Myrtle Beach (MYR) to Buffalo Niagara International Airport (BUF) every 2 hours. Alternatively, you can take a bus from Myrtle Beach Bus Station to Niagara Falls USA via Wilmington Cape Fear Public Transit, Raleigh Bus Station, and Newark Penn Station in around 25h 15m.
- Website
- aa.com
Flights from Myrtle Beach to Buffalo Niagara International Airport via Charlotte
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $95–500
Flights from Myrtle Beach to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- $90–500
Flights from Myrtle Beach to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- $100–550
Flights from Myrtle Beach to Rochester via Charlotte
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $120–650
Flights from Myrtle Beach to Rochester via Philadelphia
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $120–650
Flights from Myrtle Beach to Rochester via Reagan Washington
- Ave. Duration
- 4h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
Flights from Myrtle Beach to Toronto Pearson International Airport via Charlotte
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $60–320
Flights from Myrtle Beach to Toronto Pearson International Airport via Reagan Washington
- Ave. Duration
- 4h 37m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $60–320
- Website
- southwest.com
Flights from Myrtle Beach to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $95–500
Flights from Myrtle Beach to Buffalo Niagara International Airport via Nashville
- Ave. Duration
- 5h 12m
- When
- Tuesday to Friday
- Estimated price
- $130–650
Flights from Myrtle Beach to Rochester via Baltimore
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $120–650
- Website
- delta.com
Flights from Myrtle Beach to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 4h 1m
- When
- Tuesday to Sunday
- Estimated price
- $110–550
Flights from Myrtle Beach to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 6h 36m
- When
- Every day
- Estimated price
- $110–550
Flights from Myrtle Beach to Rochester via Detroit
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $150–750
Flights from Myrtle Beach to Toronto Pearson International Airport via Detroit
- Ave. Duration
- 6h 10m
- When
- Every day
- Estimated price
- $65–340
- Website
- flybreeze.com
Flights from Myrtle Beach to Rochester
- Ave. Duration
- 2h 5m
- When
- Thursday and Sunday
- Estimated price
- $180–700
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Charleston Amtrak Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 14h 8m
- Frequency
- Twice daily
- Estimated price
- $200–440
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Niagara Falls Amtrak Station
- Ave. Duration
- 9h 8m
- Frequency
- 3 times a day
- Estimated price
- $120–280
- Website
- Amtrak
Train from Rochester to Niagara Falls Amtrak Station
- Ave. Duration
- 2h 7m
- Frequency
- 3 times a day
- Estimated price
- $26–60
- Website
- Amtrak
Train from Fayetteville Amtrak Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 10h 53m
- Frequency
- Twice daily
- Estimated price
- $150–340
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Canadian Border
- Ave. Duration
- 9h 36m
- Frequency
- Once daily
- Estimated price
- $120–280
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Rochester to Niagara Falls Amtrak Station
- Ave. Duration
- 2h 33m
- Frequency
- Once daily
- Estimated price
- $25–170
- Website
- VIA Rail
- Escape
- $25–80
- Business
- $55–160
- Business Plus
- $65–170
- Economy
- $28–90
- Economy Plus
- $30–95
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transit
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $10–21
- Website
- Greyhound
Bus from Wilmington Cape Fear Public Transit to Raleigh Bus Station
- Ave. Duration
- 2h 55m
- Frequency
- Twice daily
- Estimated price
- $19–40
- Website
- Greyhound
Bus from Raleigh Bus Station to Newark Penn Station
- Ave. Duration
- 9h 10m
- Frequency
- 3 times a day
- Estimated price
- $65–130
- Website
- Greyhound
Bus from Myrtle Beach Bus Station to Charleston Bus Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $14–27
- Website
- Greyhound
Bus from Myrtle Beach Bus Station to Fayetteville Bus Station
- Ave. Duration
- 9h
- Frequency
- Once daily
- Estimated price
- $55–110
- Website
- Greyhound
Bus from Myrtle Beach Bus Station to Fayetteville Bus Station
- Ave. Duration
- 9h
- Frequency
- Once daily
- Estimated price
- $55–110
- Website
- Greyhound
Bus from Fayetteville to Winston-Salem
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $21–40
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Newark Penn Station to Niagara Falls USA
- Ave. Duration
- 8h 30m
- Frequency
- 3 times a day
- Estimated price
- $55–100
- Schedules at
- Flixbus USA
- Phone
- +1 866 488 4452
- [email protected]
- Website
- Megabus
Bus from Toronto Union Station to Niagara Falls, ON
- Ave. Duration
- 1h 35m
- Frequency
- Every 4 hours
- Estimated price
- $7–55
- Website
- Megabus
- Adult Advanced Booking
- $7–45
- Adult Standard
- $16–55
- Phone
- +1 704-348-1200
- [email protected]
- Website
- sunwaycharters.com
Bus from Fayetteville to Winston-Salem
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $23–35
- Schedules at
- sunwaycharters.com
- Passenger
- $23–35
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Winston Salem(Trans Center) to Columbus - Mound St
- Ave. Duration
- 9h 20m
- Frequency
- Once daily
- Estimated price
- $35–90
- Website
- Barons Bus
Bus from Columbus - Mound St to Buffalo, NY
- Ave. Duration
- 7h 15m
- Frequency
- Once daily
- Estimated price
- $35–80
- Website
- Barons Bus
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