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How to get fromMyrtle Beach to Panama City Beachby plane, bus, train, car, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Myrtle Beach to Panama City Beach by plane, bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Northwest Florida Beaches International Airport

    best
    1. Fly from Myrtle Beach (MYR) to Northwest Florida Beaches International Airport (ECP)plane plane MYR - ECP
    4h 5m
    $117–409

  2. Fly to Destin–Fort Walton Beach Airport, drive

    cheapest
    1. Fly from Myrtle Beach (MYR) to Destin–Fort Walton Beach Airport (VPS)plane plane MYR - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar car
    5h 5m
    $82–360

  3. Bus, train via Tallahassee

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    2. Take the train from Charleston Amtrak Station to Jacksonvilletrain train
    3. Take the bus from Jacksonville to Tallahasseebus bus
    4. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    16h 7m
    $145–294

  4. Drive 540 mi

    1. Drive from Myrtle Beach to Panama City Beachcar car 540 mi
    11h 9m
    $99–143

  5. Fly to Dothan Regional Airport, drive

    1. Fly from Myrtle Beach (MYR) to Dothan Regional Airport (DHN)plane plane MYR - DHN
    2. Drive from Dothan Regional Airport (DHN) to Panama City Beachcar car
    7h 48m
    $84–350

  6. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    2. Take the train from Charleston Amtrak Station to Jacksonvilletrain train
    3. Take the bus from Jacksonville to Panama City Beach Bus Stationbus bus
    16h 47m
    $145–294

  7. Bus

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Tallahasseebus bus
    3. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    19h 19m
    $120–233

Myrtle Beach (MYR) to Northwest Florida Beaches International Airport (ECP) flights

Calendar47Weekly Planes
Duration5hAverage Duration
Ticket$59Cheapest Price
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Questions & Answers

Map of how to get from Myrtle Beach to Panama City Beach.ExpandLaunch map view
  • Distance: 485.3 mi
  • Duration: 4h 5m

What companies run services between Myrtle Beach, SC, USA and Panama City Beach, FL, USA?

Delta, American Airlines, and Southwest Airlines fly from Myrtle Beach (MYR) to Northwest Florida Beaches International Airport (ECP) every 4 hours. Alternatively, you can take a bus from Myrtle Beach Bus Station to Panama City Beach via Atlanta Bus Station, Tallahassee, and Panama City Beach Bus Station in around 19h 19m.

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