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How to get fromMyrtle Beach to Port Saint Lucieby plane, taxi, bus, train, bus (Greyhound), or car

Find Transport to Port Saint Lucie

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There are 6 ways to get from Myrtle Beach to Port Saint Lucie by plane, taxi, bus, train, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Vero Beach Municipal Airport, taxi

    best
    1. Fly from Myrtle Beach (MYR) to Vero Beach Municipal Airport (VRB)plane plane MYR - VRB
    2. Take the taxi from Vero Beach Municipal Airport (VRB) to Port Saint Lucietaxi taxi
    5h 46m
    $182–554

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Myrtle Beach Bus Station to Camdenbus bus
    2. Take the bus from Camden to Jacksonvillebus bus
    3. Take the bus from Jacksonville to Port St Luciebus bus
    20h 29m
    $103–208

  3. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    2. Take the train from Charleston Amtrak Station to Kissimmee Amtrak Stationtrain train
    3. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    15h 37m
    $177–340

  4. Drive 564.9 mi

    1. Drive from Myrtle Beach to Port Saint Luciecar car 564.9 mi
    10h 8m
    $104–149

  5. Fly to Fort Lauderdale–Hollywood International Airport, bus

    1. Fly from Myrtle Beach (MYR) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane MYR - FLL
    2. Take the bus from Fort Lauderdale - Broward Blvd Park and Ride to Fort Piercebus bus
    5h 39m
    $172–609

  6. Fly to Orlando, bus

    1. Fly from Myrtle Beach (MYR) to Orlando (MCO)plane plane MYR - MCO
    2. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    6h 16m
    $126–388

Myrtle Beach to Port Saint Lucie by bus and train

Calendar7Weekly Services
Duration15h 37mAverage Duration
Ticket$177Cheapest Price
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Questions & Answers

Map of how to get from Myrtle Beach to Port Saint Lucie.ExpandLaunch map view
  • Distance: 455.9 mi
  • Duration: 5h 46m

What companies run services between Myrtle Beach, SC, USA and Port Saint Lucie, FL, USA?

You can take a bus from Myrtle Beach Bus Station to SW PSL Blvd & SE Bayshore Blvd via Camden, Jacksonville, and SW Gatlin Blvd & SW Brescia St in around 20h 29m.

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