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How to get fromMyrtle Beach to San Diegoby plane, bus (Greyhound, Amtrak), bus, train, or car

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There are 6 ways to get from Myrtle Beach to San Diego by plane, bus (Greyhound, Amtrak), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Myrtle Beach

    best
    1. Fly from Myrtle Beach (MYR) to San Diego International Airport (SAN)plane plane MYR - SAN
    6h 41m
    $192–714

  2. Bus

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Los Angeles Union Stationbus bus
    4. Take the bus from Los Angeles to San Diegobus bus
    2d 14h
    $449–867

  3. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Raleigh Bus Stationbus bus
    2. Take the train from Raleigh Union Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train
    4. Take the train from Fullerton Amtrak Station to San Diegotrain train
    3d 11h
    $1,154–2,407

  4. Drive 2,488.9 mi

    1. Drive from Myrtle Beach to San Diegocar car 2,488.9 mi
    39h 47m
    $455–657

  5. Bus to Wilmington International Airport, fly

    1. Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus bus
    2. Fly from Wilmington International Airport (ILM) to San Diego International Airport (SAN)plane plane ILM - SAN
    9h 22m
    $226–841

  6. Bus, train via Atlanta

    1. Take the bus from Myrtle Beach Bus Station to Sumter Bus Stopbus bus
    2. Take the bus from Sumter to Atlantabus bus
    3. Take the bus from Atlanta Bus Station to Springfield SMTD Transfer Centerbus bus
    4. Take the train from Springfield to Los Angelestrain train
    5. Take the bus from Los Angeles to San Diegobus bus
    3d 22h

Myrtle Beach to San Diego by bus and foot

Calendar7Weekly Services
Duration2d 14hAverage Duration
Ticket$449Cheapest Price
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Questions & Answers

Map of how to get from Myrtle Beach to San Diego.ExpandLaunch map view
  • Distance: 2,203.7 mi
  • Duration: 6h 41m

What companies run services between Myrtle Beach, SC, USA and San Diego, CA, USA?

Southwest Airlines, Delta, and two other airlines fly from Myrtle Beach (MYR) to San Diego International Airport (SAN) every 4 hours. Alternatively, you can take a bus from Myrtle Beach Bus Station to San Diego via Atlanta Bus Station, Dallas Bus Station, Los Angeles Union Station, and Los Angeles in around 2d 14h.

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