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How to get fromMyrtle Beach to Santeeby bus (Greyhound) or car

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There are 3 ways to get from Myrtle Beach to Santee by bus (Greyhound) or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Myrtle Beach Bus Station to Orangeburgbus bus Greyhound US0645S
    4h 13m
    $107–150
  2. Drive 117.9 mi

    cheapest
    1. Drive from Myrtle Beach to Santeecar car 117.9 mi
    2h 24m
    $22–32
  3. Bus via Florence

    1. Take the bus from Myrtle Beach Bus Station to Florence Bus Stationbus bus Greyhound US0641S / ...
    2. Take the bus from Florence to Orangeburgbus bus Ses 991
    4h 17m

Questions & Answers

What companies run services between Myrtle Beach, SC, USA and Santee, SC, USA?

Greyhound USA operates a bus from Myrtle Beach Bus Station to Orangeburg once daily. Tickets cost $26–55 and the journey takes 3h 45m.

Operators

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Need to know: Greyhound

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