Rome2Rio

How to get fromMyrtle Beach to Senecaby plane, taxi, bus, train, or car

Find Transport to Seneca

See all options

There are 5 ways to get from Myrtle Beach to Seneca by plane, taxi, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Greenville–Spartanburg International Airport, taxi

    best
    1. Fly from Myrtle Beach (MYR) to Greenville–Spartanburg International Airport (GSP)plane plane MYR - GSP
    2. Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi taxi
    4h 6m
    $432–1,284

  2. Drive  270.7 mi

    cheapest
    1. Drive from Myrtle Beach to Senecacar car 270.7 mi
    5h 34m
    $50–72

  3. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Take the train from Charlotte Amtrak Station to Clemson Amtrak Stationtrain train
    10h 50m
    $93–165

  4. Fly to Asheville Regional Airport, drive

    1. Fly from Myrtle Beach (MYR) to Asheville Regional Airport (AVL)plane plane MYR - AVL
    2. Drive from Asheville-Airport-AVL to Senecacar car
    4h 59m
    $64–313

  5. Bus, taxi

    1. Take the bus from Myrtle Beach Bus Station to Camdenbus bus
    2. Take the bus from Camden to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus
    4. Take the taxi from Taqueria Guadalajara - Greenville to Senecataxi taxi
    10h 51m
    $155–220

Myrtle Beach (MYR) to Greenville–Spartanburg International Airport (GSP) flights

Calendar67Weekly Planes
Duration3h 55mAverage Duration
Ticket$61Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Myrtle Beach to Seneca.ExpandLaunch map view
  • Distance: 258 mi
  • Duration: 4h 6m

What companies run services between Myrtle Beach, SC, USA and Seneca, SC, USA?

There is no direct connection from Myrtle Beach to Seneca. However, you can take the taxi to Myrtle Beach (MYR) airport, fly to Greenville–Spartanburg International Airport (GSP), then take the taxi to Seneca. Alternatively, you can take a bus from Myrtle Beach Bus Station to Seneca via Camden, Charlotte Bus Station, Trade St & Graham St, Transit Center- Bay A, CTC Station, Parkwood Station, Charlotte Amtrak Station, and Clemson Amtrak Station in around 10h 50m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound