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How to get fromMyrtle Beach to Siesta Keyby plane, bus, train, car, or bus (Greyhound, Flixbus)

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There are 5 ways to get from Myrtle Beach to Siesta Key by plane, bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Myrtle Beach (MYR) to Sarasota–Bradenton International Airport (SRQ)plane plane MYR - SRQ
    5h 7m
    $124–668

  2. Drive  576.3 mi

    cheapest
    1. Drive from Myrtle Beach to Siesta Keycar car 576.3 mi
    10h 47m
    $106–152

  3. Bus, train, drive

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    2. Take the train from Charleston Amtrak Station to Jacksonvilletrain train
    3. Take the train from Jacksonville to Tampatrain train
    4. Drive from Tampa to Siesta Keycar car
    15h 14m
    $141–330

  4. Bus

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the bus from Fayetteville Bus Station to Orlando Bus Stationbus bus
    3. Take the bus from Orlando Bus Station to Sarasota Cattlemen Transfer Centerbus bus
    20h 6m
    $127–194

  5. Bus, train, Amtrak Thruway

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    2. Take the train from Charleston Amtrak Station to Orlandotrain train
    3. Take the bus from Orlando, FL to Sarasota Amtrak Bus Stopbus bus
    17h 42m
    $150–318

Myrtle Beach to Siesta Key by bus

Calendar7Weekly Buses
Duration20h 6mAverage Duration
Ticket$127Cheapest Price
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Comparing Your Travel Options

Map of how to get from Myrtle Beach to Siesta Key.ExpandLaunch map view
  • Distance: 503 mi
  • Duration: 5h 7m

What companies run services between Myrtle Beach, SC, USA and Siesta Key, FL, USA?

Delta, American Airlines, and Southwest Airlines fly from Myrtle Beach (MYR) to Sarasota–Bradenton International Airport (SRQ) every 4 hours. Alternatively, you can take a bus from Myrtle Beach Bus Station to Ocean Blvd @ Avenida Madera via Fayetteville Bus Station, Orlando Bus Station, Sarasota Cattlemen Transfer Center, and Cattlemen Transit Station in around 20h 6m.

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