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How to get fromMyrtle Beach to Tupeloby plane, car, bus (Greyhound), or bus

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There are 6 ways to get from Myrtle Beach to Tupelo by plane, car, bus (Greyhound), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Golden Triangle Regional Airport, drive

    best
    1. Fly from Myrtle Beach (MYR) to Golden Triangle Regional Airport (GTR)plane plane MYR - GTR
    2. Drive from Golden Triangle Regional Airport (GTR) to Tupelocar car
    4h 57m
    $78–361

  2. Bus (Greyhound)

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus Greyhound US0641S
    2. Take the bus from Atlanta Bus Station to Tupelobus bus Greyhound US0610
    15h 54m
    $108–199

  3. Drive 624.8 mi

    1. Drive from Myrtle Beach to Tupelocar car 624.8 mi
    11h 9m
    $114–165

  4. Fly to Huntsville International Airport-Carl T Jones Field, drive

    1. Fly from Myrtle Beach (MYR) to Huntsville International Airport-Carl T Jones Field (HSV)plane plane MYR - HSV
    2. Drive from Huntsville International Airport-Carl T Jones Field (HSV) to Tupelocar car
    5h 41m
    $100–419

  5. Fly to Tupelo Regional Airport

    1. Fly from Myrtle Beach (MYR) to Tupelo Regional Airport (TUP)plane plane MYR - TUP
    6h 58m
    $91–372

  6. Fly to Memphis, bus

    1. Fly from Myrtle Beach (MYR) to Memphis (MEM)plane plane MYR - MEM
    2. Take the bus from Memphis Bus Station to Tupelobus bus
    7h 59m
    $139–658

Myrtle Beach (MYR) to Golden Triangle Regional Airport (GTR) flights

Calendar6Weekly Planes
Duration3h 41mAverage Duration
Ticket$59Cheapest Price
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Questions & Answers

Map of how to get from Myrtle Beach to Tupelo.ExpandLaunch map view
  • Distance: 621.2 mi
  • Duration: 4h 57m

What companies run services between Myrtle Beach, SC, USA and Tupelo, MS, USA?

You can take a bus from Myrtle Beach Bus Station to Tupelo via Atlanta Bus Station and Tupelo in around 15h 54m. Alternatively, Southwest Airlines, Corporate Flight Management Inc, and two other airlines fly from Myrtle Beach (MYR) to Tupelo Regional Airport (TUP) once daily.

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