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How to get fromMyrtle Beach to Wilkes-Barreby plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Flixbus)

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There are 6 ways to get from Myrtle Beach to Wilkes-Barre by plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Myrtle Beach (MYR) to Wilkes-Barre/Scranton International Airport (AVP)plane plane MYR - AVP
    2h 13m
    $162–629

  2. Drive 628.5 mi

    cheapest
    1. Drive from Myrtle Beach to Wilkes-Barrecar car 628.5 mi
    11h 51m
    $115–166

  3. Bus via Wilmington

    1. Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus bus
    2. Take the bus from Wilmington Cape Fear Public Transit to Raleigh Bus Stationbus bus
    3. Take the bus from Raleigh Bus Station to Port Authority Bus Terminalbus bus
    4. Take the bus from Port Authority Bus Terminal to Wilkes-Barrebus bus
    20h 25m
    $177–317

  4. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    2. Take the train from Charleston Amtrak Station to 30th Street Stationtrain train
    3. Take the bus from Philadelphia 30th St Station to Wyoming Valley Mallbus bus
    20h 26m
    $274–538

  5. Bus, train via Fayetteville

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the train from Fayetteville Amtrak Station to 30th Street Stationtrain train
    3. Take the bus from Philadelphia 30th St Station to Wilkes-Barrebus bus
    23h 48m
    $254–506

  6. Bus

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the bus from Fayetteville Bus Station to New York City Chinatownbus bus
    3. Take the bus from Port Authority Bus Terminal to Wilkes-Barrebus bus
    26h 10m
    $222–379

Myrtle Beach to Wilkes-Barre by bus

Calendar7Weekly Buses
Duration20h 25mAverage Duration
Ticket$177Cheapest Price
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Questions & Answers

Map of how to get from Myrtle Beach to Wilkes-Barre.ExpandLaunch map view
  • Distance: 571 mi
  • Duration: 2h 13m

What companies run services between Myrtle Beach, SC, USA and Wilkes-Barre, PA, USA?

Breeze Airways and United Airlines fly from Myrtle Beach (MYR) to Wilkes-Barre/Scranton International Airport (AVP) once daily. Alternatively, you can take a bus from Myrtle Beach Bus Station to Wilkes-Barre via Wilmington Cape Fear Public Transit, Raleigh Bus Station, and Port Authority Bus Terminal in around 20h 25m.

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