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How to get fromMystic to Syracuseby train, bus, train (Amtrak), car, or plane

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There are 10 ways to get from Mystic to Syracuse by train, bus, train (Amtrak), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus via New York

    best
    1. Take the train from Mystic Station to Ny Moynihan Train Hall At Penn Stationtrain train Northeast Regional
    2. Take the bus from New York Midtown to Syracuse Bus Stationbus bus FlixBus N2686 / ...
    9h 13m
    $82–164
  2. Train, bus

    cheapest
    1. Take the train from Mystic Station to Old Saybrook Amtrak Stationtrain train
    2. Take the bus from Old Saybrook Trans Cntr to Asylum St @ Union Plbus bus 921
    3. Take the bus from Hartford to Springfieldbus bus
    4. Take the bus from Springfield Union Station to Syracuse Bus Stationbus bus
    9h 49m
    $44–104
  3. Train (Amtrak)

    1. Take the train from Mystic Station to Ny Moynihan Train Hall At Penn Stationtrain train Northeast Regional
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Syracuse Regional Transportation Centertrain train Empire Service / ...
    9h 42m
    $132–279
  4. Drive 297.5 mi

    1. Drive from Mystic to Syracusecar car 297.5 mi
    5h 38m
    $55–79
  5. Train to Boston Logan Airport, fly to Syracuse Hancock International Airport

    1. Take the train from Mystic Station to Bostontrain train
    2. Fly from Boston Logan Airport (BOS) to Syracuse Hancock International Airport (SYR)plane plane BOS - SYR
    6h 12m
    $120–629
  6. Train via Albany

    1. Take the train from Mystic Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Albany-Rensselaer Amtrak Stationtrain train
    3. Take the train from Albany-Rensselaer Amtrak Station to Syracuse Regional Transportation Centertrain train
    10h 15m
    $122–374
  7. Train, train to Laguardia Airport, fly to Syracuse Hancock International Airport

    1. Take the train from Mystic Station to Stamford Amtrak Stationtrain train
    2. Take the train from Stamford to 125th Street - Harlemtrain train
    3. Fly from Laguardia Airport (LGA) to Syracuse Hancock International Airport (SYR)plane plane LGA - SYR
    7h 45m
    $135–748
  8. Train to John F. Kennedy International Airport, fly to Syracuse Hancock International Airport

    1. Take the train from Mystic Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Syracuse Hancock International Airport (SYR)plane plane JFK - SYR
    7h 52m
    $127–616
  9. Train to Boston Logan Airport, fly to Rochester, train

    1. Take the train from Mystic Station to Bostontrain train
    2. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    3. Take the train from Rochester to Syracuse Regional Transportation Centertrain train
    7h 10m
    $163–863
  10. Train, train to Laguardia Airport, fly to Rochester

    1. Take the train from Mystic Station to Stamford Amtrak Stationtrain train
    2. Take the train from Stamford to 125th Street - Harlemtrain train
    3. Fly from Laguardia Airport (LGA) to Rochester (ROC)plane plane LGA - ROC
    4. Take the train from Rochester to Syracuse Regional Transportation Centertrain train
    8h 36m
    $178–932

Mystic to Syracuse by train and bus

Calendar26Weekly Services
Duration9h 13mAverage Duration
Ticket$82Cheapest Price
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Questions & Answers

What companies run services between Mystic, CT, USA and Syracuse, NY, USA?

You can take a train from Mystic Station to Syracuse Regional Transportation Center via Ny Moynihan Train Hall At Penn Station in around 9h 42m.

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