There are 10 ways to get from Mystic to Syracuse by train, bus, train (Amtrak), car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus via New York
best- Take the train from Mystic Station to Ny Moynihan Train Hall At Penn Stationtrain Northeast Regional
- Take the bus from New York Midtown to Syracuse Bus Stationbus FlixBus N2686 / ...
9h 13m$82–164Train, bus
cheapest- Take the train from Mystic Station to Old Saybrook Amtrak Stationtrain
- Take the bus from Old Saybrook Trans Cntr to Asylum St @ Union Plbus 921
- Take the bus from Hartford to Springfieldbus
- Take the bus from Springfield Union Station to Syracuse Bus Stationbus
9h 49m$44–104Train (Amtrak)
- Take the train from Mystic Station to Ny Moynihan Train Hall At Penn Stationtrain Northeast Regional
- Take the train from Ny Moynihan Train Hall At Penn Station to Syracuse Regional Transportation Centertrain Empire Service / ...
9h 42m$132–279Drive 297.5 mi
- Drive from Mystic to Syracusecar 297.5 mi
5h 38m$55–79Train to Boston Logan Airport, fly to Syracuse Hancock International Airport
- Take the train from Mystic Station to Bostontrain
- Fly from Boston Logan Airport (BOS) to Syracuse Hancock International Airport (SYR)plane BOS - SYR
6h 12m$120–629Train via Albany
- Take the train from Mystic Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Albany-Rensselaer Amtrak Stationtrain
- Take the train from Albany-Rensselaer Amtrak Station to Syracuse Regional Transportation Centertrain
10h 15m$122–374Train, train to Laguardia Airport, fly to Syracuse Hancock International Airport
- Take the train from Mystic Station to Stamford Amtrak Stationtrain
- Take the train from Stamford to 125th Street - Harlemtrain
- Fly from Laguardia Airport (LGA) to Syracuse Hancock International Airport (SYR)plane LGA - SYR
7h 45m$135–748Train to John F. Kennedy International Airport, fly to Syracuse Hancock International Airport
- Take the train from Mystic Station to Ny Moynihan Train Hall At Penn Stationtrain
- Fly from John F. Kennedy International Airport (JFK) to Syracuse Hancock International Airport (SYR)plane JFK - SYR
7h 52m$127–616Train to Boston Logan Airport, fly to Rochester, train
- Take the train from Mystic Station to Bostontrain
- Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane BOS - ROC
- Take the train from Rochester to Syracuse Regional Transportation Centertrain
7h 10m$163–863Train, train to Laguardia Airport, fly to Rochester
- Take the train from Mystic Station to Stamford Amtrak Stationtrain
- Take the train from Stamford to 125th Street - Harlemtrain
- Fly from Laguardia Airport (LGA) to Rochester (ROC)plane LGA - ROC
- Take the train from Rochester to Syracuse Regional Transportation Centertrain
8h 36m$178–932
Mystic to Syracuse by train and bus
Questions & Answers
The cheapest way to get from Mystic to Syracuse is to train and bus which costs $40 - $110 and takes 9h 49m.
The fastest way to get from Mystic to Syracuse is to drive which takes 5h 38m and costs $50 - $80.
No, there is no direct train from Mystic station to Syracuse. However, there are services departing from Mystic Station and arriving at Syracuse Regional Transportation Center via Ny Moynihan Train Hall At Penn Station. The journey, including transfers, takes approximately 9h 42m.
The distance between Mystic and Syracuse is 422 miles. The road distance is 299.2 miles.
The best way to get from Mystic to Syracuse without a car is to train and bus via New York which takes 9h 13m and costs $80 - $170.
It takes approximately 9h 13m to get from Mystic to Syracuse, including transfers.
Mystic to Syracuse train services, operated by Amtrak, depart from Mystic Station.
Mystic to Syracuse train services, operated by Amtrak, arrive at Ny Moynihan Train Hall At Penn Station.
Yes, the driving distance between Mystic to Syracuse is 299 miles. It takes approximately 5h 38m to drive from Mystic to Syracuse.
Book your Mystic to Syracuse train tickets online with Omio.
What companies run services between Mystic, CT, USA and Syracuse, NY, USA?
You can take a train from Mystic Station to Syracuse Regional Transportation Center via Ny Moynihan Train Hall At Penn Station in around 9h 42m.
- Website
- delta.com
Flights from Laguardia Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $90–650
Flights from John F. Kennedy International Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $70–500
Flights from Boston Logan Airport to Rochester via Laguardia Airport
- Ave. Duration
- 3h 47m
- When
- Monday to Friday
- Estimated price
- $100–600
Flights from Laguardia Airport to Rochester
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $95–650
- Website
- aa.com
Flights from Boston Logan Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $80–550
Flights from Boston Logan Airport to Rochester
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $85–600
- Website
- southwest.com
Flights from Boston Logan Airport to Rochester via Baltimore
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $120–700
- Website
- united.com
Flights from Boston Logan Airport to Rochester via Washington Dulles
- Ave. Duration
- 3h 53m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $130–700
Flights from Laguardia Airport to Rochester via Washington Dulles
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $130–800
- Website
- jetblue.com
Flights from Boston Logan Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $80–550
Flights from John F. Kennedy International Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $70–500
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Mystic Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 3m
- Frequency
- 4 times a day
- Estimated price
- $40–90
- Website
- Amtrak
Train from Mystic Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 3m
- Frequency
- 4 times a day
- Estimated price
- $40–90
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Syracuse Regional Transportation Center
- Ave. Duration
- 5h 39m
- Frequency
- 4 times a day
- Estimated price
- $90–190
- Website
- Amtrak
Train from Mystic Station to Boston
- Ave. Duration
- 1h 30m
- Frequency
- 5 times a day
- Estimated price
- $29–65
- Website
- Amtrak
Train from Mystic Station to Old Saybrook Amtrak Station
- Ave. Duration
- 32 min
- Frequency
- 3 times a day
- Estimated price
- $8–18
- Website
- Amtrak
Train from Mystic Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 3m
- Frequency
- 4 times a day
- Estimated price
- $40–90
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Albany-Rensselaer Amtrak Station
- Ave. Duration
- 2h 31m
- Frequency
- Hourly
- Estimated price
- $40–95
- Website
- Amtrak
Train from Albany-Rensselaer Amtrak Station to Syracuse Regional Transportation Center
- Ave. Duration
- 2h 46m
- Frequency
- 5 times a day
- Estimated price
- $45–100
- Website
- Amtrak
Train from Mystic Station to Stamford Amtrak Station
- Ave. Duration
- 2h 3m
- Frequency
- 4 times a day
- Estimated price
- $30–65
- Website
- Amtrak
Train from Mystic Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 3m
- Frequency
- 4 times a day
- Estimated price
- $40–90
- Website
- Amtrak
Train from Mystic Station to Boston
- Ave. Duration
- 1h 30m
- Frequency
- 5 times a day
- Estimated price
- $29–65
- Website
- Amtrak
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- 5 times a day
- Estimated price
- $24–55
- Website
- Amtrak
Train from Mystic Station to Stamford Amtrak Station
- Ave. Duration
- 2h 3m
- Frequency
- 4 times a day
- Estimated price
- $30–65
- Website
- Amtrak
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- 5 times a day
- Estimated price
- $24–55
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Albany-Rensselaer Amtrak Station to Syracuse Regional Transportation Center
- Ave. Duration
- 2h 39m
- Frequency
- Once daily
- Estimated price
- $40–190
- Website
- VIA Rail
- Escape
- $40–110
- Business
- $70–180
- Business Plus
- $85–190
- Economy
- $45–120
- Economy Plus
- $50–130
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $21–170
- Website
- VIA Rail
- Escape
- $21–75
- Business
- $50–150
- Business Plus
- $65–170
- Economy
- $24–80
- Economy Plus
- $26–90
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $21–170
- Website
- VIA Rail
- Escape
- $21–75
- Business
- $50–150
- Business Plus
- $65–170
- Economy
- $24–80
- Economy Plus
- $26–90
- Phone
- +1 877.690.5114
- Website
- Metro North Railroad
Train from Stamford to 125th Street - Harlem
- Ave. Duration
- 58 min
- Frequency
- Every 15 minutes
- Estimated price
- $10–17
- Website
- Metro North Railroad
- Schedules at
- Metro North Railroad Schedules
- Off-Peak
- $10–12
- Peak
- $14–17
Train from Stamford to 125th Street - Harlem
- Ave. Duration
- 58 min
- Frequency
- Every 15 minutes
- Estimated price
- $10–17
- Website
- Metro North Railroad
- Schedules at
- Metro North Railroad Schedules
- Off-Peak
- $10–12
- Peak
- $14–17
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from New York Midtown to Syracuse Bus Station
- Ave. Duration
- 5h 10m
- Frequency
- Every 4 hours
- Estimated price
- $40–75
- Schedules at
- Flixbus USA
Bus from Springfield Union Station to Syracuse Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- 3 times a week
- Estimated price
- $35–60
- Schedules at
- Flixbus USA
- Phone
- +1 860-525-9181
- Website
- CT Transit
Bus from Old Saybrook Trans Cntr to Asylum St @ Union Pl
- Ave. Duration
- 1h 7m
- Frequency
- 4 times a day
- Estimated price
- $2–6
- Website
- CT Transit
- Book at
- CT Transit Bookings
- Two-Hour Pass
- $2
- Two-Hour Pass express
- $5–6
- Phone
- 1-800-343-9999
- Website
- Peter Pan
Bus from Hartford to Springfield
- Ave. Duration
- 35 min
- Frequency
- Every 4 hours
- Estimated price
- $5–15
- Website
- Peter Pan
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Springfield Union Station to Syracuse Bus Station
- Ave. Duration
- 4h 35m
- Frequency
- Twice daily
- Estimated price
- $30–65
- Website
- Greyhound
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