Rome2Rio

How to get fromNacogdoches to St. Louisby car, plane, bus, train, or bus (Greyhound, Flixbus)

Find Transport to St. Louis

See all options

There are 7 ways to get from Nacogdoches to St. Louis by car, plane, bus, train, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Tyler, fly

    best
    1. Drive from Nacogdoches to Tyler (TYR)car car
    2. Fly from Tyler (TYR) to Lambert–St. Louis International Airport (STL)plane plane TYR - STL
    6h 20m
    $118–575

  2. Drive 634.8 mi

    cheapest
    1. Drive from Nacogdoches to St. Louiscar car 634.8 mi
    11h 43m
    $116–168

  3. Bus, train (Amtrak)

    1. Take the bus from Nacogdoches Amtrak Bus Stop to Longviewbus bus Amtrak Thruway Connecting Service
    2. Take the train from Longview to St. Louistrain train Texas Eagle
    15h 37m
    $227–441

  4. Bus

    1. Take the bus from Nacogdoches to Texarkanabus bus
    2. Take the bus from Texarkana to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to St Louis Bus Stationbus bus
    16h 33m
    $133–260

  5. Bus to Gregg County Airport, fly

    1. Take the bus from Nacogdoches to Longview Bus Stationbus bus
    2. Fly from Gregg County Airport (GGG) to Lambert–St. Louis International Airport (STL)plane plane GGG - STL
    7h 36m
    $145–611

  6. Bus to William P. Hobby Airport, fly

    1. Take the bus from Nacogdoches to Houston Bus Stationbus bus
    2. Fly from William P. Hobby Airport (HOU) to Lambert–St. Louis International Airport (STL)plane plane HOU - STL
    7h 35m
    $210–965

  7. Bus to George Bush Intercontinental Airport, fly

    1. Take the bus from Nacogdoches to Houston Bus Stationbus bus
    2. Fly from George Bush Intercontinental Airport (IAH) to Lambert–St. Louis International Airport (STL)plane plane IAH - STL
    8h 35m
    $332–1,020

Tyler (TYR) to Lambert–St. Louis International Airport (STL) flights

Calendar14Weekly Planes
Duration4h 22mAverage Duration
Ticket$105Cheapest Price
See schedules

Questions & Answers

Map of how to get from Nacogdoches to St. Louis.ExpandLaunch map view
  • Distance: 620.1 mi
  • Duration: 6h 20m

What companies run services between Nacogdoches, TX, USA and St. Louis, MO, USA?

You can take a vehicle from Nacogdoches to St Louis Bus Station via Nacogdoches, Texarkana, and Memphis Bus Station in around 16h 33m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers