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How to get fromNaperville to Florenceby train, plane, bus, train (Amtrak), car, or bus (Greyhound, Flixbus)

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There are 10 ways to get from Naperville to Florence by train, plane, bus, train (Amtrak), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Chicago O'Hare International Airport, fly to Myrtle Beach, bus

    best
    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Myrtle Beach (MYR)plane plane ORD - MYR
    3. Take the bus from Myrtle Beach Bus Station to Florence Bus Stationbus bus
    8h 9m
    $85–344

  2. Train, bus

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Take the bus from Chicago to Columbusbus bus
    3. Take the bus from Columbus to Charlottebus bus
    4. Take the bus from Charlotte Bus Station to Camdenbus bus
    5. Take the bus from Camden to Florence Bus Stationbus bus
    25h 38m
    $103–222

  3. Train

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    3. Take the train from Raleigh Union Station to Selma Stationtrain train
    4. Take the train from Selma Station to Florence Stationtrain train
    31h 18m
    $640–1,051

  4. Drive  861.9 mi

    1. Drive from Naperville to Florencecar car 861.9 mi
    15h 46m
    $148–213

  5. Train to Chicago Midway International Airport, fly to Charleston International Airport, train

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Charleston International Airport (CHS)plane plane MDW - CHS
    3. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    9h 54m
    $171–745

  6. Train to Chicago O'Hare International Airport, fly to Charleston International Airport, train

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Charleston International Airport (CHS)plane plane ORD - CHS
    3. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    10h 5m
    $561–945

  7. Train to Chicago O'Hare International Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Charlotte Douglas International Airport (CLT)plane plane ORD - CLT
    3. Take the bus from Charlotte Bus Station to Camdenbus bus
    4. Take the bus from Camden to Florence Bus Stationbus bus
    10h 30m
    $119–543

  8. Train to Chicago Midway International Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Charlotte Douglas International Airport (CLT)plane plane MDW - CLT
    3. Take the bus from Charlotte Bus Station to Camdenbus bus
    4. Take the bus from Camden to Florence Bus Stationbus bus
    10h 22m
    $174–853

  9. Train to Chicago O'Hare International Airport, fly to Columbia, bus

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Columbia (CAE)plane plane ORD - CAE
    3. Take the bus from Columbia, SC to Camdenbus bus
    4. Take the bus from Camden to Florence Bus Stationbus bus
    11h 7m
    $103–389

  10. Bus

    1. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta Bus Station to Florence Bus Stationbus bus Greyhound US0641S / ...
    27h 16m
    $171–292

Naperville to Florence by train, foot, and bus

Calendar7Weekly Services
Duration25h 38mAverage Duration
Ticket$103Cheapest Price
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Comparing Your Travel Options

Map of how to get from Naperville to Florence.ExpandLaunch map view
  • Distance: 870.5 mi
  • Duration: 8h 9m

What companies run services between Naperville, IL, USA and Florence, SC, USA?

You can take a train from Naperville to Florence Station via Chicago Union Station, Raleigh Union Station, and Selma Station in around 31h 18m. Alternatively, you can take a bus from Washington St & Ogden Ave to Florence Bus Station via Yorktown Center, 54th/Cermak Pink Line Station, Cicero & 24th Place Terminal, Jefferson & Harrison, Chicago Bus Station, and Atlanta Bus Station in around 27h 16m.

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