There are 5 ways to get from Naperville to Kirksville by train (Amtrak), car, bus, plane, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Naperville Amtrak Station to La Plata Stationtrain Southwest Chief
4h 36m$133–231Drive 314.4 mi
cheapest- Drive from Naperville to Kirksvillecar 314.4 mi
6h 59m$58–83Line 330 bus, fly to Kirksville Regional Airport
- Take the bus from La Grange/Burlington Ave. to Rosemont CTA Stationbus
- Fly from Chicago O'Hare International Airport (ORD) to Kirksville Regional Airport (IRK)plane ORD - IRK
4h 24m$108–248Fly to Columbia Regional Airport, shuttle
- Fly from Chicago O'Hare International Airport (ORD) to Columbia Regional Airport (COU)plane ORD - COU
- Take a shuttle bus from Columbia to Hy-Vee - Kirksville
6h 55m$107–384Fly to Burlington Municipal Airport, drive
- Fly from Chicago O'Hare International Airport (ORD) to Burlington Municipal Airport (BRL)plane ORD - BRL
- Drive from Burlington Municipal Airport (BRL) to Kirksvillecar
6h 50m$84–178
Chicago O'Hare International Airport (ORD) to Kirksville Regional Airport (IRK) flights
Questions & Answers
The cheapest way to get from Naperville to Kirksville is to drive which costs $55 - $85 and takes 6h 59m.
The fastest way to get from Naperville to Kirksville is to line 330 bus and fly which takes 4h 24m and costs $100 - $250.
No, there is no direct train from Naperville station to Kirksville station. However, there are services departing from Naperville Amtrak Station and arriving at La Plata Station via . The journey, including transfers, takes approximately 4h 36m.
The distance between Naperville and Kirksville is 284 miles. The road distance is 316.2 miles.
The best way to get from Naperville to Kirksville without a car is to train which takes 4h 36m and costs $130 - $240.
It takes approximately 4h 36m to get from Naperville to Kirksville, including transfers.
Naperville to Kirksville train services, operated by Amtrak, depart from Naperville Amtrak Station.
Naperville to Kirksville train services, operated by Amtrak, arrive at La Plata Station.
Yes, the driving distance between Naperville to Kirksville is 316 miles. It takes approximately 6h 59m to drive from Naperville to Kirksville.
Book your Naperville to Kirksville train tickets online with Omio.
What companies run services between Naperville, IL, USA and Kirksville, MO, USA?
Amtrak operates a train from Naperville Amtrak Station to La Plata Station once daily. Tickets cost $85–180 and the journey takes 4h 19m.
- Website
- contouraviation.com
Flights from Chicago O'Hare International Airport to Kirksville Regional Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $65–190
Flights from Chicago O'Hare International Airport to Burlington Municipal Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $55–130
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Columbia Regional Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $45–300
- Website
- united.com
Flights from Chicago O'Hare International Airport to Columbia Regional Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $45–300
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Naperville Amtrak Station to La Plata Station
- Ave. Duration
- 4h 19m
- Frequency
- Once daily
- Estimated price
- $85–180
- Website
- https://www.amtrak.com/home.html
- Phone
- +1(847) 364-7223
- [email protected]
- Website
- pacebus.com
Bus from La Grange/Burlington Ave. to Rosemont CTA Station
- Ave. Duration
- 42 min
- Frequency
- Hourly
- Estimated price
- $2–3
- Website
- https://www.pacebus.com
- Schedules at
- https://www.pacebus.com/routes-schedules-and-maps
- Adult
- $2–3
- Phone
- +1-888-875-6287
- Website
- oatstransit.org
Shuttle from Columbia to Hy-Vee - Kirksville
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $4–6
- Website
- https://www.oatstransit.org
- Schedules at
- https://www.oatstransit.org/schedules
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There are 10+ hotels available in Kirksville.