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How to get fromNaperville to Knoxvilleby bus, plane, train, bus (Flixbus), or car

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There are 8 ways to get from Naperville to Knoxville by bus, plane, train, bus (Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 330 bus to Chicago O'Hare International Airport, fly to Mcghee Tyson Airport

    best
    1. Take the bus from La Grange/Burlington Ave. to Rosemont CTA Stationbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS)plane plane ORD - TYS
    4h 44m
    $163–683

  2. Fly Chicago O'Hare International Airport to Asheville Regional Airport, drive

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)plane plane ORD - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    6h 47m
    $90–388

  3. Train, bus

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    35h 49m
    $498–909

  4. Bus

    1. Take the bus from Naperville to Chicagobus bus
    2. Take the bus from Chicago Bus Station to New York City Chinatownbus bus
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    39h 22m
    $278–401

  5. Drive 543.9 mi

    1. Drive from Naperville to Knoxvillecar car 543.9 mi
    9h 39m
    $100–144

  6. Train to Chicago Midway International Airport, fly to Mcghee Tyson Airport

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Mcghee Tyson Airport (TYS)plane plane MDW - TYS
    4h 51m
    $192–881

  7. Fly Chicago O'Hare International Airport to Chattanooga Metropolitan Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Chattanooga Metropolitan Airport (CHA)plane plane ORD - CHA
    2. Drive from Chattanooga Metropolitan Airport (CHA) to Knoxvillecar car
    6h 13m
    $136–691

  8. Train, bus via Ossining

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    3. Take the train from Croton-Harmon to 125th Street - Harlemtrain train
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    36h 26m
    $453–836

Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS) flights

Calendar75Weekly Planes
Duration2h 58mAverage Duration
Ticket$108Cheapest Price
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Questions & Answers

Map of how to get from Naperville to Knoxville.ExpandLaunch map view
  • Distance: 518.7 mi
  • Duration: 4h 44m

What companies run services between Naperville, IL, USA and Knoxville, TN, USA?

You can take a bus from Naperville to Knoxville Station Hall of Fame via Chicago Bus Station, New York, NY, Knoxville, TN, Walmart, and Fountain City Superstop in around 39h 22m.

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