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How to get fromNaperville to Knoxvilleby train, plane, bus, or car

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There are 9 ways to get from Naperville to Knoxville by train, plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Chicago O'Hare International Airport, fly to Mcghee Tyson Airport

    best
    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS)plane plane ORD - TYS
    5h 8m
    $172–731

  2. Train to Chicago O'Hare International Airport, fly to Chattanooga Metropolitan Airport, drive

    cheapest
    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Chattanooga Metropolitan Airport (CHA)plane plane ORD - CHA
    3. Drive from Chattanooga Metropolitan Airport (CHA) to Knoxvillecar car
    6h 43m
    $80–359

  3. Train, bus

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    35h 49m
    $438–859

  4. Train, bus via New York

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Take the bus from Chicago Bus Station to New York Midtownbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    35h 59m
    $328–499

  5. Drive  543.9 mi

    1. Drive from Naperville to Knoxvillecar car 543.9 mi
    9h 39m
    $100–144

  6. Train to Chicago Midway International Airport, fly to Mcghee Tyson Airport

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Mcghee Tyson Airport (TYS)plane plane MDW - TYS
    4h 46m
    $202–981

  7. Train to Chicago O'Hare International Airport, fly to Asheville Regional Airport, drive

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)plane plane ORD - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar car
    7h 6m
    $84–376

  8. Train, bus via Ossining

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    3. Take the train from Croton-Harmon to 125th Street - Harlemtrain train
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    36h 27m
    $393–736

  9. Train, bus #2

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Take the bus from Chicago Bus Station to New York City Chinatownbus bus
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    39h 59m
    $244–361

Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS) flights

Calendar79Weekly Planes
Duration2h 42mAverage Duration
Ticket$110Cheapest Price
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Questions & Answers

Map of how to get from Naperville to Knoxville.ExpandLaunch map view
  • Distance: 535.2 mi
  • Duration: 5h 8m

What companies run services between Naperville, IL, USA and Knoxville, TN, USA?

There is no direct connection from Naperville to Knoxville. However, you can take the train to Chicago Union Station, walk to LaSalle, take the subway to O'Hare, walk to Chicago O'Hare International Airport (ORD) airport, fly to Mcghee Tyson Airport (TYS), then take the taxi to Knoxville. Alternatively, you can take a train from Naperville to Knoxville via Chicago Union Station, Ny Moynihan Train Hall At Penn Station, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 35h 49m.

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