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How to get fromNaperville to La Crosseby train (Amtrak), bus (Greyhound, Flixbus), car, bus, or plane

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There are 5 ways to get from Naperville to La Crosse by train (Amtrak), bus (Greyhound, Flixbus), car, bus, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Naperville to Chicago Union Stationtrain train Bnsf
    2. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train Empire Builder / ...
    7h 3m
    $95–196

  2. Drive 268.2 mi

    cheapest
    1. Drive from Naperville to La Crossecar car 268.2 mi
    4h 39m
    $49–71

  3. Bus

    1. Take the bus from Naperville to Chicagobus bus
    2. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    3. Take the bus from Milwaukee to La Crossebus bus
    8h 2m

  4. Line 330 bus, fly

    1. Take the bus from La Grange/Burlington Ave. to Rosemont CTA Stationbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to La Crosse (LSE)plane plane ORD - LSE
    4h 17m
    $67–316

  5. Bus via Madison

    1. Take the bus from Multi-Modal/Rental Car Facility to 250 N. Lake St - Madison UW Campusbus bus Van Galder
    2. Take the bus from Madison to La Crossebus bus Jefferson 966 / ...
    8h 15m
    $64–114

Naperville to La Crosse by train

Calendar21Weekly Trains
Duration7h 3mAverage Duration
Ticket$95Cheapest Price
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Questions & Answers

Map of how to get from Naperville to La Crosse.ExpandLaunch map view
  • Distance: 308.2 mi
  • Duration: 7h 3m

What companies run services between Naperville, IL, USA and La Crosse, WI, USA?

You can take a train from Naperville to La Crosse Amtrak Station via Chicago Union Station in around 7h 3m. Alternatively, you can take a bus from Naperville to La Crosse via Chicago Bus Station, Milwaukee Intermodal Station, and Milwaukee in around 8h 2m.

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