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How to get fromNaperville to Louisvilleby train, bus, car, or plane

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There are 7 ways to get from Naperville to Louisville by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus via Chicago

    best
    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Take the bus from Chicago Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    8h 43m
    $55–106

  2. Train, bus

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    10h 23m
    $87–181

  3. Drive 311.9 mi

    1. Drive from Naperville to Louisvillecar car 311.9 mi
    5h 32m
    $57–83

  4. Line 330 bus to Chicago O'Hare International Airport, fly to Louisville International Airport

    1. Take the bus from La Grange/Burlington Ave. to Rosemont CTA Stationbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    5h 23m
    $74–426

  5. Train to Chicago Midway International Airport, fly to Louisville International Airport

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    5h 26m
    $88–564

  6. Fly Chicago O'Hare International Airport to Blue Grass Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane plane ORD - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    5h 32m
    $121–682

  7. Fly Chicago O'Hare International Airport to Covington, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Covington (CVG)plane plane ORD - CVG
    2. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus
    7h 55m
    $169–860

Naperville to Louisville by train, foot, and bus

Calendar14Weekly Services
Duration8h 43mAverage Duration
Ticket$55Cheapest Price
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Questions & Answers

Map of how to get from Naperville to Louisville.ExpandLaunch map view
  • Distance: 323.6 mi
  • Duration: 8h 43m

What companies run services between Naperville, IL, USA and Louisville, KY, USA?

There is no direct connection from Naperville to Louisville. However, you can take the train to Chicago Union Station, walk to Chicago Bus Station, take the bus to Indianapolis Union Station, then take the bus to Louisville, KY. Alternatively, you can take a train from Naperville to Louisville, KY via Chicago Union Station, Indianapolis, and Indianapolis Union Station in around 10h 23m.

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