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How to get fromNaperville to Muscatineby train, car, bus, taxi, or plane

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There are 6 ways to get from Naperville to Muscatine by train, car, bus, taxi, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, drive (Amtrak)

    best
    1. Take the train from Naperville Amtrak Station to Galesburg Amtrak Stationtrain train Southwest Chief / ...
    2. Drive from Galesburg Amtrak Station to Muscatinecar car
    3h 47m
    $53–103

  2. Drive 172.2 mi

    cheapest
    1. Drive from Naperville to Muscatinecar car 172.2 mi
    3h 4m
    $32–46

  3. Train, bus, taxi

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Take the bus from Chicago Bus Station to Moline Center Stationbus bus
    3. Take the taxi from Moline Center Station to Muscatinetaxi taxi
    7h 16m
    $130–176

  4. Train, fly to Quad City International Airport, taxi

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Quad City International Airport (MLI)plane plane ORD - MLI
    3. Take the taxi from Moline-Airport-MLI to Muscatinetaxi taxi
    5h 1m
    $142–391

  5. Train, fly to The Eastern Iowa Airport, drive

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to The Eastern Iowa Airport (CID)plane plane ORD - CID
    3. Drive from Cedar-Rapids-Airport-CID to Muscatinecar car
    5h 37m
    $52–297

  6. Train, fly to Burlington Municipal Airport, drive

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Burlington Municipal Airport (BRL)plane plane ORD - BRL
    3. Drive from Burlington Municipal Airport (BRL) to Muscatinecar car
    5h 37m
    $66–155

Chicago O'Hare International Airport (ORD) to Quad City International Airport (MLI) flights

Calendar60Weekly Planes
Duration1h 13mAverage Duration
Ticket$35Cheapest Price
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Questions & Answers

Map of how to get from Naperville to Muscatine.ExpandLaunch map view
  • Distance: 201.1 mi
  • Duration: 3h 47m

What companies run services between Naperville, IL, USA and Muscatine, IA, USA?

There is no direct connection from Naperville to Muscatine. However, you can take the train to Galesburg Amtrak Station then drive to Muscatine. Alternatively, you can take the train to Chicago Union Station, walk to Chicago Bus Station, take the bus to Moline Center Station, then take the taxi to Muscatine.

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