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How to get fromNaperville to Sikestonby train, plane, taxi, bus, or car

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There are 6 ways to get from Naperville to Sikeston by train, plane, taxi, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, fly to Cape Girardeau Municipal Airport, taxi

    best
    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI)plane plane ORD - CGI
    3. Take the taxi from Cape Girardeau Municipal Airport (CGI) to Sikestontaxi taxi
    5h 11m
    $187–521

  2. Train, fly to Barkley Regional Airport, drive

    cheapest
    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Barkley Regional Airport (PAH)plane plane ORD - PAH
    3. Drive from Barkley Regional Airport (PAH) to Sikestoncar car
    5h 46m
    $57–306

  3. Train, bus

    1. Take the train from Naperville to Chicago Union Stationtrain train Bnsf
    2. Take the bus from Tornado Bus Co - Chicago to Flying J - Matthewsbus bus Milwaukee
    10h 28m
    $119–154

  4. Train, drive

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Fulton Amtrak Stationtrain train
    3. Drive from Fulton Amtrak Station to Sikestoncar car
    11h 20m
    $127–315

  5. Drive  387.4 mi

    1. Drive from Naperville to Sikestoncar car 387.4 mi
    6h 56m
    $71–103

  6. Train, fly to Williamson County Regional Airport, bus

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA)plane plane ORD - MWA
    3. Take the bus from Marathon Gas Station - Marion to Flying J - Matthewsbus bus
    7h 26m
    $142–312

Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI) flights

Calendar7Weekly Planes
Duration1h 35mAverage Duration
Ticket$107Cheapest Price
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Comparing Your Travel Options

Map of how to get from Naperville to Sikeston.ExpandLaunch map view
  • Distance: 415.6 mi
  • Duration: 5h 11m

What companies run services between Naperville, IL, USA and Sikeston, MO, USA?

There is no direct connection from Naperville to Sikeston. However, you can take the train to Chicago Union Station, walk to Jackson-Blue, take the subway to O'Hare, walk to Chicago O'Hare International Airport (ORD) airport, fly to Cape Girardeau Municipal Airport (CGI), then take the taxi to Sikeston. Alternatively, you can take a train from Naperville to Sikeston via Chicago Union Station, LaSalle/Van Buren, 35th/Archer, 35th/Archer Orange Line Station, California & 35th Street, Tornado Bus Co - Chicago, and Flying J - Matthews in around 10h 28m.

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