Rome2Rio

How to get fromNaperville to Sikestonby bus, plane, taxi, train, or car

Find Transport to Sikeston

See all options

There are 7 ways to get from Naperville to Sikeston by bus, plane, taxi, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 330 bus, fly to Cape Girardeau Municipal Airport, taxi

    best
    1. Take the bus from La Grange/Burlington Ave. to Rosemont CTA Stationbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI)plane plane ORD - CGI
    3. Take the taxi from Cape Girardeau Municipal Airport (CGI) to Sikestontaxi taxi
    4h 53m
    $183–323
  2. Fly to Barkley Regional Airport, drive

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Barkley Regional Airport (PAH)plane plane ORD - PAH
    2. Drive from Barkley Regional Airport (PAH) to Sikestoncar car
    5h 23m
    $63–338
  3. Train, bus

    1. Take the train from Naperville to Chicago Union Stationtrain train Bnsf
    2. Take the bus from Tornado Bus Co - Chicago to Flying J - Matthewsbus bus Milwaukee
    10h 32m
    $114–244
  4. Train, drive

    1. Take the train from Naperville to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Fulton Amtrak Stationtrain train
    3. Drive from Fulton Amtrak Station to Sikestoncar car
    11h 20m
    $147–295
  5. Drive 388.2 mi

    1. Drive from Naperville to Sikestoncar car 388.2 mi
    6h 53m
    $71–103
  6. Fly to Williamson County Regional Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA)plane plane ORD - MWA
    2. Take the bus from Marathon Gas Station - Marion to Flying J - Matthewsbus bus
    6h 53m
    $171–424
  7. Fly to Lambert–St. Louis International Airport, bus, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    3. Take the taxi from Cape Girardeau to Sikestontaxi taxi
    8h 18m
    $389–871

Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI) flights

Calendar7Weekly Planes
Duration1h 40mAverage Duration
Ticket$99Cheapest Price
See schedules

Questions & Answers

What companies run services between Naperville, IL, USA and Sikeston, MO, USA?

There is no direct connection from Naperville to Sikeston. However, you can take the train to LaGrange Road, walk to La Grange/Burlington Ave., take the line 330 bus to Rosemont CTA Station, walk to Rosemont, take the subway to O'Hare, walk to Chicago O'Hare International Airport (ORD) airport, fly to Cape Girardeau Municipal Airport (CGI), then take the taxi to Sikeston. Alternatively, you can take a train from Naperville to Sikeston via Union Station, LaSalle/Van Buren, 35th/Archer, 35th/Archer Orange Line Station, California & 35th Street, Tornado Bus Co - Chicago, and Flying J - Matthews in around 10h 32m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound