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How to get fromNaples to Des Moinesby bus, plane, bus (Flixbus, Greyhound), train, car, or taxi

Find Transport to Des Moines

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There are 7 ways to get from Naples to Des Moines by bus, plane, bus (Flixbus, Greyhound), train, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Sarasota–Bradenton International Airport, fly

    best
    1. Take the bus from Naples, FL to Bradenton/Sarasota - Mobil Gas Stationbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Des Moines (DSM)plane plane SRQ - DSM
    8h 7m
    $289–1,207

  2. Bus, bus to Fort Lauderdale–Hollywood International Airport, fly

    cheapest
    1. Take the bus from Naples, FL to Miami Airportbus bus
    2. Take the bus from Miami Airport to Fort Lauderdale Airportbus bus
    3. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Des Moines (DSM)plane plane FLL - DSM
    8h 26m
    $263–961

  3. Bus

    1. Take the bus from Naples, FL to University of South Florida - 3801 USF Holly Drbus bus
    2. Take the bus from University of South Florida to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Des Moinesbus bus
    34h 27m
    $278–527

  4. Bus, train

    1. Take the bus from Naples, FL to Fort Myers 7-11bus bus
    2. Take the bus from Fort Myers Amtrak Bus Stop to Orlandobus bus
    3. Take the train from Orlando to Chicago Union Stationtrain train
    4. Take the bus from Chicago Bus Station to Des Moinesbus bus
    2d 7h
    $707–1,455

  5. Drive 1,470.5 mi

    1. Drive from Naples to Des Moinescar car 1,470.5 mi
    26h 6m
    $269–388

  6. Line 11 bus, line 600 bus, line 240 bus to Ft. Myers, fly

    1. Take the bus from 3rd Ave S to Creekside WLinCbus bus
    2. Take the bus from Creekside Way Transfer @ Immokalee Rd to Coconut Point Mallbus bus
    3. Take the bus from Coconut Point Mall to South Fort Myers Transfer/P&Rbus bus
    4. Fly from Ft. Myers (RSW) to Des Moines (DSM)plane plane RSW - DSM
    9h 13m

  7. Taxi to Punta Gorda Airport, fly

    1. Take the taxi from South Fort Myers Transfer/P&R to Punta Gorda Airport (PGD)taxi taxi
    2. Fly from Punta Gorda Airport (PGD) to Des Moines (DSM)plane plane PGD - DSM
    8h 10m
    $290–987

Sarasota–Bradenton International Airport (SRQ) to Des Moines (DSM) flights

Calendar43Weekly Planes
Duration5h 21mAverage Duration
Ticket$229Cheapest Price
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Questions & Answers

Map of how to get from Naples to Des Moines.ExpandLaunch map view
  • Distance: 1,303.6 mi
  • Duration: 8h 7m

What companies run services between Naples, FL, USA and Des Moines, IA, USA?

You can take a vehicle from Naples to Des Moines via Naples, FL, University of South Florida, Atlanta Bus Station, and St Louis Bus Station in around 34h 27m.

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