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How to get fromNaples to Florida Keysby ferry, bus (Greyhound), or car

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There are 3 ways to get from Naples to Florida Keys by ferry, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Ferry

    best
    1. Take the ferry from Marco Island, FL to Key West, FLferry ferry Key West
    6h 20m
    $182–195
  2. Drive 222.3 mi

    cheapest
    1. Drive from Naples to Florida Keyscar car 222.3 mi
    4h 50m
    $41–59
  3. Bus

    1. Take the bus from Naples to Miami Airportbus bus Miami–Tallahassee via Tampa / ...
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus Greyhound US0720s
    8h 38m
    $75–131

Questions & Answers

What companies run services between Naples, FL, USA and Florida Keys, FL, USA?

Key West Express operates a ferry from Marco Island, FL to Key West, FL once daily. Tickets cost $130 and the journey takes 4h. Alternatively, you can take a vehicle from Naples to Florida Keys via Naples, Miami Airport, Miami International Airport, Miami, Airport Intermodal Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 8h 38m.

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