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How to get fromNaples to Lake Cityby bus (Greyhound), car, bus, plane, or bus (Flixbus, Greyhound)

Find Transport to Lake City

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There are 6 ways to get from Naples to Lake City by bus (Greyhound), car, bus, plane, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Naples, FL to University of Florida - 1956 Gale Lemerand Drbus bus Miami
    2. Take the bus from Gainesville Bus Stop to Lake City Bus Stationbus bus Greyhound US0630
    9h 36m
    $101–191

  2. Drive 304.5 mi

    cheapest
    1. Drive from Naples to Lake Citycar car 304.5 mi
    5h 45m
    $56–81

  3. Bus, fly to Jacksonville

    1. Take the bus from Naples, FL to Miami Airportbus bus
    2. Fly from Miami International Airport (MIA) to Jacksonville (JAX)plane plane MIA - JAX
    3. Take the bus from Jacksonville to Lake City Bus Stationbus bus
    8h 14m
    $110–433

  4. Bus via University

    1. Take the bus from Naples, FL to University of South Florida - 3801 USF Holly Drbus bus
    2. Take the bus from University of South Florida to Gainesvillebus bus
    3. Take the bus from Gainesville Bus Stop to Lake City Bus Stationbus bus
    9h 47m
    $90–161

  5. Bus via Orlando

    1. Take the bus from Fort Myers Bus Stop to Orlando Bus Stationbus bus FlixBus 2421
    2. Take the bus from Orlando Bus Station to Lake City Bus Stationbus bus Greyhound US0630
    15h 9m
    $62–114

  6. Bus, fly to Tallahassee

    1. Take the bus from Naples, FL to Miami Airportbus bus
    2. Fly from Miami International Airport (MIA) to Tallahassee (TLH)plane plane MIA - TLH
    3. Take the bus from Tallahassee to Lake City Bus Stationbus bus
    8h 16m
    $153–530

Naples to Lake City by bus

Calendar14Weekly Buses
Duration15h 9mAverage Duration
Ticket$62Cheapest Price
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Questions & Answers

Map of how to get from Naples to Lake City.ExpandLaunch map view
  • Distance: 353.9 mi
  • Duration: 9h 36m

What companies run services between Naples, FL, USA and Lake City, FL, USA?

You can take a vehicle from Naples to Lake City Bus Station via Naples, FL, University of Florida - 1956 Gale Lemerand Dr, UF Health Archer Road, North Walmart Supercenter, and Gainesville Bus Stop in around 9h 36m.

Airlines
Bus operators

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Need to know: Greyhound

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