There are 8 ways to get from Naples to Murrells Inlet by plane, bus, train, car, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Naples Municipal Airport
best- Fly from Naples Municipal Airport (APF) to Myrtle Beach (MYR)plane APF - MYR
6h 36m$112–421Bus, train, drive
- Take the bus from Naples, FL to Miami Airportbus
- Take the train from Hollywood Amtrak Station to Kingstree Stationtrain
- Drive from Kingstree Station to Murrells Inletcar
19h 55m$444–690Bus, train
- Take the bus from Naples, FL to Fort Myers 7-11bus
- Take the bus from Fort Myers Amtrak Bus Stop to Orlandobus
- Take the train from Orlando to Charleston Amtrak Stationtrain
- Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus
20h 23mDrive 643.2 mi
- Drive from Naples to Murrells Inletcar 643.2 mi
11h 58m$118–170Bus, bus to Fort Lauderdale–Hollywood International Airport, fly
- Take the bus from Naples, FL to Miami Airportbus
- Take the bus from Miami Airport to Fort Lauderdale Airportbus
- Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Myrtle Beach (MYR)plane FLL - MYR
7h 3m$276–536Bus to Tampa, fly
- Take the bus from Naples, FL to University of South Florida - 3801 USF Holly Drbus
- Fly from Tampa (TPA) to Myrtle Beach (MYR)plane TPA - MYR
8h 42m$196–483Fly from Ft. Myers
- Fly from Ft. Myers (RSW) to Myrtle Beach (MYR)plane RSW - MYR
10h 20m$120–458Bus
- Take the bus from Naples, FL to Miami Airportbus
- Take the bus from Miami Airport Station to Fayetteville Bus Stationbus
- Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus
23h 10m$237–342
Naples Municipal Airport (APF) to Myrtle Beach (MYR) flights
Comparing Your Travel Options
The cheapest way to get from Naples to Murrells Inlet is to drive which costs $110 - $170 and takes 11h 58m.
The fastest way to get from Naples to Murrells Inlet is to fly which takes 6h 36m and costs $110 - $430.
No, there is no direct bus from Naples to Murrells Inlet station. However, there are services departing from Naples, FL and arriving at Myrtle Beach Bus Station via Miami Airport Station and Fayetteville Bus Station. The journey, including transfers, takes approximately 23h 10m.
The distance between Naples and Murrells Inlet is 569 miles. The road distance is 646.9 miles.
The best way to get from Naples to Murrells Inlet without a car is to bus and train which takes 20h 23m and costs .
It takes approximately 6h 36m to get from Naples to Murrells Inlet, including transfers.
Naples to Murrells Inlet bus services, operated by RedCoach, depart from Naples, FL station.
The best way to get from Naples to Murrells Inlet is to fly which takes 6h 36m and costs $110 - $430. Alternatively, you can bus, which costs $230 - $350 and takes 23h 10m.
Naples to Murrells Inlet bus services, operated by RedCoach, arrive at Miami Airport station.
Yes, the driving distance between Naples to Murrells Inlet is 647 miles. It takes approximately 11h 58m to drive from Naples to Murrells Inlet.
What companies run services between Naples, FL, USA and Murrells Inlet, SC, USA?
American Airlines flies from Naples Municipal Airport (APF) to Myrtle Beach (MYR) twice daily. Alternatively, you can take a vehicle from Naples to Murrells Inlet via Naples, FL, Miami Airport, Miami International Airport, Miami, Airport Intermodal Station, Miami Airport Station, Fayetteville Bus Station, and Myrtle Beach Bus Station in around 23h 10m.
- Website
- aa.com
Flights from Naples Municipal Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 5h 44m
- When
- Every day
- Estimated price
- $70–380
Flights from Fort Lauderdale–Hollywood International Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $75–410
Flights from Tampa to Myrtle Beach via Charlotte
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $60–350
Flights from Ft. Myers to Myrtle Beach via Charlotte
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $75–400
- Website
- delta.com
Flights from Fort Lauderdale–Hollywood International Airport to Myrtle Beach via Atlanta
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $85–430
Flights from Tampa to Myrtle Beach via Atlanta
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- $65–360
Flights from Ft. Myers to Myrtle Beach via Atlanta
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $80–420
- Website
- southwest.com
Flights from Fort Lauderdale–Hollywood International Airport to Myrtle Beach via Nashville
- Ave. Duration
- 4h 45m
- When
- Tuesday and Wednesday
- Estimated price
- $100–500
Flights from Ft. Myers to Myrtle Beach via Nashville
- Ave. Duration
- 5h 51m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $100–480
Flights from Ft. Myers to Myrtle Beach via Baltimore
- Ave. Duration
- 5h 12m
- When
- Tuesday to Friday
- Estimated price
- $110–500
- Website
- flybreeze.com
Flights from Fort Lauderdale–Hollywood International Airport to Myrtle Beach
- Ave. Duration
- 1h 57m
- When
- Every day
- Estimated price
- $180–410
Flights from Tampa to Myrtle Beach
- Ave. Duration
- 1h 38m
- When
- Monday, Wednesday, Friday, Saturday, Thursday, and Sunday
- Estimated price
- $90–340
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Hollywood Amtrak Station to Kingstree Station
- Ave. Duration
- 13h 56m
- Frequency
- Once daily
- Estimated price
- $380–600
- Website
- Amtrak
Train from Orlando to Charleston Amtrak Station
- Ave. Duration
- 7h 49m
- Frequency
- Once daily
- Estimated price
- $220–340
- Website
- Amtrak
- Phone
- +1 877 733 0724
- Website
- RedCoach
Bus from Naples, FL to Miami Airport
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $27–40
- Website
- RedCoach
Bus from Naples, FL to Fort Myers 7-11
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Estimated price
- $9–14
- Website
- RedCoach
Bus from Naples, FL to Miami Airport
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $27–40
- Website
- RedCoach
Bus from Miami Airport to Fort Lauderdale Airport
- Ave. Duration
- 30 min
- Frequency
- 5 times a day
- Estimated price
- $6–9
- Website
- RedCoach
Bus from Naples, FL to University of South Florida - 3801 USF Holly Dr
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- $40–60
- Website
- RedCoach
Bus from Naples, FL to Miami Airport
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $27–40
- Website
- RedCoach
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Fort Myers Amtrak Bus Stop to Orlando
- Ave. Duration
- 5h 50m
- Frequency
- Once daily
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Charleston Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $17–26
- Website
- Greyhound
Bus from Fayetteville Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- $27–40
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Miami Airport Station to Fayetteville Bus Station
- Ave. Duration
- 15h 20m
- Frequency
- 4 times a week
- Estimated price
- $120–180
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
Booking & Getting There
There are 3262+ hotels available in Murrells Inlet.










