There are 8 ways to get from Naples to Murrells Inlet by bus, plane, train, car, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, bus to Fort Lauderdale–Hollywood International Airport, fly to Myrtle Beach
best- Take the bus from Naples, FL to Miami Airportbus
- Take the bus from Miami Airport to Fort Lauderdale Airportbus
- Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Myrtle Beach (MYR)plane FLL - MYR
6h 58m$236–536Drive 643.2 mi
cheapest- Drive from Naples to Murrells Inletcar 643.2 mi
11h 58m$118–170Bus, train, drive
- Take the bus from Naples, FL to Miami Airportbus
- Take the train from Hollywood Amtrak Station to Kingstree Stationtrain
- Drive from Kingstree Station to Murrells Inletcar
19h 55m$244–490Bus, train
- Take the bus from Naples, FL to Fort Myers 7-11bus
- Take the bus from Fort Myers Amtrak Bus Stop to Orlandobus
- Take the train from Orlando to Charleston Amtrak Stationtrain
- Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus
20h 13m$242–436Bus to Tampa, fly to Myrtle Beach
- Take the bus from Naples, FL to University of South Florida - 3801 USF Holly Drbus
- Fly from Tampa (TPA) to Myrtle Beach (MYR)plane TPA - MYR
8h 42m$196–483Fly Ft. Myers to Myrtle Beach
- Fly from Ft. Myers (RSW) to Myrtle Beach (MYR)plane RSW - MYR
10h 37m$120–488Bus, shuttle to Orlando, fly to Myrtle Beach
- Take the bus from Naples, FL to Ocala, FLbus
- Take a shuttle bus from Sleep Inn to Orlando Airport
- Fly from Orlando (MCO) to Myrtle Beach (MYR)plane MCO - MYR
9h 51m$293–442Bus to Miami International Airport, fly to Charleston International Airport, bus
- Take the bus from Naples, FL to Miami Airportbus
- Fly from Miami International Airport (MIA) to Charleston International Airport (CHS)plane MIA - CHS
- Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus
10h 47m$599–1,151
Fort Lauderdale–Hollywood International Airport (FLL) to Myrtle Beach (MYR) flights
Comparing Your Travel Options
The cheapest way to get from Naples to Murrells Inlet is to drive which costs $110 - $170 and takes 11h 58m.
The fastest way to get from Naples to Murrells Inlet is to bus and fly which takes 6h 58m and costs $230 - $550.
The distance between Naples and Murrells Inlet is 691 miles. The road distance is 646.9 miles.
The best way to get from Naples to Murrells Inlet without a car is to bus and train which takes 20h 13m and costs $240 - $440.
It takes approximately 6h 58m to get from Naples to Murrells Inlet, including transfers.
Yes, the driving distance between Naples to Murrells Inlet is 647 miles. It takes approximately 11h 58m to drive from Naples to Murrells Inlet.
There are 3229+ hotels available in Murrells Inlet.
What companies run services between Naples, FL, USA and Murrells Inlet, SC, USA?
American Airlines, Southwest Airlines, and Delta fly from Ft. Myers (RSW) to Myrtle Beach (MYR) every 3 hours.
- Website
- aa.com
Flights from Fort Lauderdale–Hollywood International Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $75–400
Flights from Tampa to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $60–350
Flights from Ft. Myers to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $75–430
Flights from Orlando to Myrtle Beach via Charlotte
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $55–330
Flights from Miami International Airport to Charleston International Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $65–410
Flights from Miami International Airport to Charleston International Airport via Charlotte
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $90–480
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Hollywood Amtrak Station to Kingstree Station
- Ave. Duration
- 13h 56m
- Frequency
- Once daily
- Estimated price
- $180–400
- Website
- Amtrak
Train from Orlando to Charleston Amtrak Station
- Ave. Duration
- 7h 49m
- Frequency
- Once daily
- Estimated price
- $100–230
- Website
- Amtrak
- Phone
- +1 877 733 0724
- Website
- RedCoach
Bus from Naples, FL to Miami Airport
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $27–40
- Website
- RedCoach
Bus from Miami Airport to Fort Lauderdale Airport
- Ave. Duration
- 30 min
- Frequency
- 5 times a day
- Estimated price
- $6–9
- Website
- RedCoach
Bus from Naples, FL to Miami Airport
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $27–40
- Website
- RedCoach
Bus from Naples, FL to Fort Myers 7-11
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Estimated price
- $9–14
- Website
- RedCoach
Bus from Naples, FL to University of South Florida - 3801 USF Holly Dr
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- $40–60
- Website
- RedCoach
Bus from Naples, FL to Ocala, FL
- Ave. Duration
- 4h 35m
- Frequency
- Once daily
- Estimated price
- $60–85
- Website
- RedCoach
Bus from Naples, FL to Miami Airport
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $27–40
- Website
- RedCoach
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