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How to get fromNaples to St. Louisby bus, plane, bus (Flixbus, Greyhound), car, or bus (Greyhound)

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There are 9 ways to get from Naples to St. Louis by bus, plane, bus (Flixbus, Greyhound), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Fort Lauderdale–Hollywood International Airport, fly to Lambert–St. Louis International Airport

    best
    1. Take the bus from Naples to Fort Lauderdale Airportbus bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Lambert–St. Louis International Airport (STL)plane plane FLL - STL
    6h 11m
    $551–1,180

  2. Drive 1,140.3 mi

    cheapest
    1. Drive from Naples to St. Louiscar car 1,140.3 mi
    19h 32m
    $209–301

  3. Bus

    1. Take the bus from Naples to Tampa USFbus bus
    2. Take the bus from University of South Florida to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    23h 47m
    $218–397

  4. Bus to Miami International Airport, fly to Lambert–St. Louis International Airport

    1. Take the bus from Naples to Miami Airportbus bus
    2. Fly from Miami International Airport (MIA) to Lambert–St. Louis International Airport (STL)plane plane MIA - STL
    6h 50m
    $606–1,040

  5. Bus to Tampa, fly to Lambert–St. Louis International Airport

    1. Take the bus from Naples to Tampa Airportbus bus
    2. Fly from Tampa (TPA) to Lambert–St. Louis International Airport (STL)plane plane TPA - STL
    7h 26m
    $486–2,110

  6. Bus to Sarasota–Bradenton International Airport, fly to Lambert–St. Louis International Airport

    1. Take the bus from Naples, FL to Bradenton/Sarasota - Mobil Gas Stationbus bus
    2. Fly from Sarasota–Bradenton International Airport (SRQ) to Lambert–St. Louis International Airport (STL)plane plane SRQ - STL
    7h 53m
    $216–889

  7. Bus to Punta Gorda Airport, fly to Midamerica St. Louis Airport

    1. Take the bus from Naples to Fort Myersbus bus
    2. Fly from Punta Gorda Airport (PGD) to Midamerica St. Louis Airport (BLV)plane plane PGD - BLV
    5h 53m
    $223–602

  8. Line 11 bus, line 600 bus, line 240 bus to Ft. Myers, fly to Lambert–St. Louis International Airport

    1. Take the bus from 3rd Ave S to Creekside WLinCbus bus
    2. Take the bus from Creekside Way Transfer @ Immokalee Rd to Coconut Point Mallbus bus
    3. Take the bus from Coconut Point Mall to South Fort Myers Transfer/P&Rbus bus
    4. Fly from Ft. Myers (RSW) to Lambert–St. Louis International Airport (STL)plane plane RSW - STL
    8h 59m

  9. Bus via Nashville

    1. Take the bus from Naples to Tallahassee FSUbus bus
    2. Take the bus from Tallahassee to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to Evansville Bus Stationbus bus
    4. Take the bus from Evansville Bus Station to St Louis Bus Stationbus bus
    28h 51m
    $260–489

Fort Lauderdale–Hollywood International Airport (FLL) to Lambert–St. Louis International Airport (STL) flights

Calendar58Weekly Planes
Duration4h 15mAverage Duration
Ticket$144Cheapest Price
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Questions & Answers

Map of how to get from Naples to St. Louis.ExpandLaunch map view
  • Distance: 1,179.2 mi
  • Duration: 6h 11m

What companies run services between Naples, FL, USA and St. Louis, MO, USA?

You can take a vehicle from Naples to St Louis Bus Station via Naples, University of South Florida, and Atlanta Bus Station in around 23h 47m.

Airlines
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