Rome2Rio

How to get fromNaples to Knoxvilleby plane, car, or train

Find Transport to Knoxville

See all options

There are 6 ways to get from Naples to Knoxville by plane, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Naples Airport to Mcghee Tyson Airport

    best
    1. Fly from Naples Airport (NAP) to Mcghee Tyson Airport (TYS)plane plane NAP - TYS
    13h 55m
    $752–2,560

  2. Fly Naples Airport to Asheville Regional Airport, drive

    cheapest
    1. Fly from Naples Airport (NAP) to Asheville Regional Airport (AVL)plane plane NAP - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    15h 53m
    $350–1,209

  3. Fly Naples Airport to Chattanooga Metropolitan Airport, drive

    1. Fly from Naples Airport (NAP) to Chattanooga Metropolitan Airport (CHA)plane plane NAP - CHA
    2. Drive from Chattanooga Metropolitan Airport (CHA) to Knoxvillecar car
    16h 10m
    $362–1,252

  4. Fly Naples Airport to Hartsfield-Jackson Atlanta International Airport, drive

    1. Fly from Naples Airport (NAP) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane NAP - ATL
    2. Drive from Atlanta-Airport-ATL to Knoxvillecar car
    15h 17m
    $481–1,306

  5. Fly Naples Airport to Greenville–Spartanburg International Airport, drive

    1. Fly from Naples Airport (NAP) to Greenville–Spartanburg International Airport (GSP)plane plane NAP - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Knoxvillecar car
    17h 8m
    $534–1,852

  6. Train to Fiumicino International Airport, fly to Mcghee Tyson Airport

    1. Take the train from Napoli to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Mcghee Tyson Airport (TYS)plane plane FCO - TYS
    16h 36m
    $688–2,323

Naples Airport (NAP) to Mcghee Tyson Airport (TYS) flights

Calendar26Weekly Planes
Duration15h 5mAverage Duration
Ticket$696Cheapest Price
See schedules

Questions & Answers

Map of how to get from Naples to Knoxville.ExpandLaunch map view
  • Distance: 5,047.2 mi
  • Duration: 13h 55m

What companies run services between Naples, Italy and Knoxville, TN, USA?

Delta, American Airlines, and three other airlines fly from Naples Airport (NAP) to Mcghee Tyson Airport (TYS) 4 times a day.

Airlines
Train operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Italy Travel Guides

Read the travel guideItaly Travel Guides