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How to get fromNashua to St. Louisby plane, bus, train, bus (Flixbus, Greyhound), car, or bus (Greyhound, Flixbus)

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There are 6 ways to get from Nashua to St. Louis by plane, bus, train, bus (Flixbus, Greyhound), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Manchester Airport

    best
    1. Fly from Manchester Airport (MHT) to Lambert–St. Louis International Airport (STL)plane plane MHT - STL
    5h 26m
    $263–959

  2. Route 3, bus via New York

    cheapest
    1. Take the bus from Nashua, NH to Boston South Busesbus bus
    2. Take the bus from Boston to New York Midtownbus bus
    3. Take the bus from Port Authority Bus Terminal to St Louis Bus Stationbus bus
    30h 50m
    $205–385

  3. Bus, train (Amtrak)

    1. Take the bus from Nashua, NH to Boston South Busesbus bus
    2. Take the train from Boston to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    30h 18m
    $435–912

  4. Drive 1,160.2 mi

    1. Drive from Nashua to St. Louiscar car 1,160.2 mi
    20h 44m
    $212–306

  5. Route 3 to Boston Logan Airport, fly

    1. Take the bus from Nashua, NH to Boston Logan Airport Terminal Cbus bus
    2. Fly from Boston Logan Airport (BOS) to Lambert–St. Louis International Airport (STL)plane plane BOS - STL
    6h 18m
    $379–875

  6. Route 3, bus

    1. Take the bus from Nashua, NH to Boston South Busesbus bus
    2. Take the bus from Boston to Newark Penn Stationbus bus
    3. Take the bus from Newark Penn Station to St Louis Bus Stationbus bus
    31h 15m
    $205–400

Nashua to St. Louis by bus and train (Amtrak)

Calendar7Weekly Services
Duration30h 18mAverage Duration
Ticket$435Cheapest Price
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Questions & Answers

Map of how to get from Nashua to St. Louis.ExpandLaunch map view
  • Distance: 1,056.2 mi
  • Duration: 5h 26m

What companies run services between Nashua, NH, USA and St. Louis, MO, USA?

Southwest Airlines, American Airlines, and United Airlines fly from Manchester Airport (MHT) to Lambert–St. Louis International Airport (STL) every 2 hours. Alternatively, you can take a bus from Nashua, NH to St Louis Bus Station via Boston South Buses, Boston, New York Midtown, and Port Authority Bus Terminal in around 30h 50m.

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