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How to get fromNatchez to Knoxvilleby car, plane, train, bus, taxi, or shuttle

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There are 9 ways to get from Natchez to Knoxville by car, plane, train, bus, taxi, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Baton Rouge Metropolitan Airport, fly

    best
    1. Drive from Natchez to Baton-Rouge-Airport-BTRcar car
    2. Fly from Baton Rouge Metropolitan Airport (BTR) to Mcghee Tyson Airport (TYS)plane plane BTR - TYS
    5h 32m
    $210–892

  2. Drive  591.6 mi

    cheapest
    1. Drive from Natchez to Knoxvillecar car 591.6 mi
    10h 19m
    $108–156

  3. Drive, train, bus, taxi, shuttle via Atlanta

    1. Drive from Natchez to Brookhaven Stationcar car
    2. Take the train from Brookhaven Station to Jacksontrain train
    3. Take the bus from Jackson to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Charlotte Bus Stationbus bus
    5. Take the bus from Charlotte to Boonebus bus
    6. Take the taxi from Boone to Black Bear Resorttaxi taxi
    7. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    8. Drive from Hot Springs to Chilhowee at Holstoncar car
    26h 28m
    $408–543

  4. Drive, train, bus, taxi, shuttle

    1. Drive from Natchez to Brookhaven Stationcar car
    2. Take the train from Brookhaven Station to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to High Pointtrain train
    4. Take the bus from Forsyth Hospital to Boonebus bus
    5. Take the taxi from Boone to Black Bear Resorttaxi taxi
    6. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    7. Drive from Hot Springs to Knoxvillecar car
    35h 29m
    $547–920

  5. Taxi to Alexandria International Airport, fly

    1. Take the taxi from Natchez to Alexandria International Airport (AEX)taxi taxi
    2. Fly from Alexandria International Airport (AEX) to Mcghee Tyson Airport (TYS)plane plane AEX - TYS
    5h 54m
    $227–946

  6. Fly from Natchez

    1. Fly from Natchez (HEZ) to Mcghee Tyson Airport (TYS)plane plane HEZ - TYS
    6h 56m
    $283–1,103

  7. Taxi to Monroe Regional Airport, fly

    1. Take the taxi from Natchez to Monroe Regional Airport (MLU)taxi taxi
    2. Fly from Monroe Regional Airport (MLU) to Mcghee Tyson Airport (TYS)plane plane MLU - TYS
    6h 8m
    $217–896

  8. Drive, train to Jackson/Vicksburg, fly

    1. Drive from Natchez to Brookhaven Stationcar car
    2. Take the train from Brookhaven Station to Jacksontrain train
    3. Fly from Jackson/Vicksburg (JAN) to Mcghee Tyson Airport (TYS)plane plane JAN - TYS
    7h 53m
    $236–922

  9. Taxi to Lafayette Regional Airport, fly

    1. Take the taxi from Natchez to Lafayette Regional Airport (LFT)taxi taxi
    2. Fly from Lafayette Regional Airport (LFT) to Mcghee Tyson Airport (TYS)plane plane LFT - TYS
    7h 25m
    $227–946

Baton Rouge Metropolitan Airport (BTR) to Mcghee Tyson Airport (TYS) flights

Calendar18Weekly Planes
Duration4h 18mAverage Duration
Ticket$144Cheapest Price
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Questions & Answers

Map of how to get from Natchez to Knoxville.ExpandLaunch map view
  • Distance: 649.1 mi
  • Duration: 5h 32m

What companies run services between Natchez, MS, USA and Knoxville, TN, USA?

United Airlines and Allegiant Air fly from Natchez (HEZ) to Mcghee Tyson Airport (TYS) once daily.

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