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How to get fromNatchez to Knoxvilleby taxi, plane, bus, shuttle, car, or train

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There are 8 ways to get from Natchez to Knoxville by taxi, plane, bus, shuttle, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Alexandria International Airport, fly

    best
    1. Take the taxi from Natchez to Alexandria International Airport (AEX)taxi taxi
    2. Fly from Alexandria International Airport (AEX) to Mcghee Tyson Airport (TYS)plane plane AEX - TYS
    6h
    $207–796

  2. Drive 591.6 mi

    cheapest
    1. Drive from Natchez to Knoxvillecar car 591.6 mi
    10h 19m
    $108–156

  3. Bus, taxi, shuttle, drive

    1. Take the bus from Natchez to Baton Rougebus bus
    2. Take the bus from Baton Rouge Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Charlotte Bus Stationbus bus
    4. Take the bus from Charlotte to Boonebus bus
    5. Take the taxi from Boone to Black Bear Resorttaxi taxi
    6. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    7. Drive from Hot Springs to Chilhowee at Holstoncar car
    28h 17m
    $507–683

  4. Bus, train, taxi, shuttle, drive

    1. Take the bus from Natchez to Baton Rougebus bus
    2. Take the bus from Baton Rouge Bus Station to New Orleans Bus Stationbus bus
    3. Take the train from New Orleans Union Passenger Terminal to High Pointtrain train
    4. Take the bus from Forsyth Hospital to Boonebus bus
    5. Take the taxi from Boone to Black Bear Resorttaxi taxi
    6. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    7. Drive from Hot Springs to Knoxvillecar car
    36h 8m
    $637–1,050

  5. Taxi to Monroe Regional Airport, fly

    1. Take the taxi from Natchez to Monroe Regional Airport (MLU)taxi taxi
    2. Fly from Monroe Regional Airport (MLU) to Mcghee Tyson Airport (TYS)plane plane MLU - TYS
    6h 14m
    $197–796

  6. Fly from Natchez

    1. Fly from Natchez (HEZ) to Mcghee Tyson Airport (TYS)plane plane HEZ - TYS
    7h 34m
    $263–953

  7. Drive, train to Jackson/Vicksburg, fly

    1. Drive from Natchez to Brookhaven Stationcar car
    2. Take the train from Brookhaven Station to Jacksontrain train
    3. Fly from Jackson/Vicksburg (JAN) to Mcghee Tyson Airport (TYS)plane plane JAN - TYS
    7h 11m
    $229–822

  8. Bus to Baton Rouge Metropolitan Airport, fly

    1. Take the bus from Natchez to Baton Rougebus bus
    2. Fly from Baton Rouge Metropolitan Airport (BTR) to Mcghee Tyson Airport (TYS)plane plane BTR - TYS
    9h 18m
    $227–841

Alexandria International Airport (AEX) to Mcghee Tyson Airport (TYS) flights

Calendar45Weekly Planes
Duration4h 59mAverage Duration
Ticket$132Cheapest Price
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Questions & Answers

Map of how to get from Natchez to Knoxville.ExpandLaunch map view
  • Distance: 675.1 mi
  • Duration: 6h

What companies run services between Natchez, MS, USA and Knoxville, TN, USA?

United Airlines flies from Natchez (HEZ) to Mcghee Tyson Airport (TYS) 4 times a week.

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