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How to get fromNatchez to Louisvilleby plane, car, train, bus, or taxi

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There are 9 ways to get from Natchez to Louisville by plane, car, train, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Natchez

    best
    1. Fly from Natchez (HEZ) to Louisville International Airport (SDF)plane plane HEZ - SDF
    6h 42m
    $169–686

  2. Drive, train, bus via Nashville

    cheapest
    1. Drive from Natchez to Brookhaven Stationcar car
    2. Take the train from Brookhaven Station to Jacksontrain train
    3. Take the bus from Jackson to Memphis Bus Stationbus bus
    4. Take the bus from Memphis Bus Station to Nashville Bus Stationbus bus
    5. Take the bus from Nashville to Louisville, KYbus bus
    16h 15m
    $119–237

  3. Drive, train, bus via Memphis

    1. Drive from Natchez to Brookhaven Stationcar car
    2. Take the train from Brookhaven Station to Jacksontrain train
    3. Take the bus from Jackson to Memphis Bus Stationbus bus
    4. Take the bus from Tornado Bus Co - West Memphis to La Tropicana - Louisville, KYbus bus
    16h 8m
    $175–365

  4. Drive, train, bus

    1. Drive from Natchez to Brookhaven Stationcar car
    2. Take the train from Brookhaven Station to Champaign-Urbanatrain train
    3. Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    21h 56m
    $273–552

  5. Drive 656 mi

    1. Drive from Natchez to Louisvillecar car 656 mi
    12h 31m
    $120–173

  6. Drive to Baton Rouge Metropolitan Airport, fly

    1. Drive from Natchez to Baton-Rouge-Airport-BTRcar car
    2. Fly from Baton Rouge Metropolitan Airport (BTR) to Louisville International Airport (SDF)plane plane BTR - SDF
    7h 9m
    $126–625

  7. Taxi to Alexandria International Airport, fly

    1. Take the taxi from Natchez to Alexandria International Airport (AEX)taxi taxi
    2. Fly from Alexandria International Airport (AEX) to Louisville International Airport (SDF)plane plane AEX - SDF
    7h 18m
    $133–629

  8. Taxi to Monroe Regional Airport, fly

    1. Take the taxi from Natchez to Monroe Regional Airport (MLU)taxi taxi
    2. Fly from Monroe Regional Airport (MLU) to Louisville International Airport (SDF)plane plane MLU - SDF
    8h 32m
    $133–629

  9. Drive, train to Jackson/Vicksburg, fly

    1. Drive from Natchez to Brookhaven Stationcar car
    2. Take the train from Brookhaven Station to Jacksontrain train
    3. Fly from Jackson/Vicksburg (JAN) to Louisville International Airport (SDF)plane plane JAN - SDF
    8h 48m
    $150–580

Natchez (HEZ) to Louisville International Airport (SDF) flights

Calendar14Weekly Planes
Duration6h 22mAverage Duration
Ticket$141Cheapest Price
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Questions & Answers

Map of how to get from Natchez to Louisville.ExpandLaunch map view
  • Distance: 568.5 mi
  • Duration: 6h 42m

What companies run services between Natchez, MS, USA and Louisville, KY, USA?

United Airlines flies from Natchez (HEZ) to Louisville International Airport (SDF) twice daily.

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