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How to get fromNatchez to Louisvilleby plane, car, train, bus, or taxi

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There are 10 ways to get from Natchez to Louisville by plane, car, train, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Natchez

    best
    1. Fly from Natchez (HEZ) to Louisville International Airport (SDF)plane plane HEZ - SDF
    5h 53m
    $179–786

  2. Drive  656 mi

    cheapest
    1. Drive from Natchez to Louisvillecar car 656 mi
    12h 31m
    $120–173

  3. Drive, train, bus via New South Memphis

    1. Drive from Natchez to Brookhaven Stationcar car
    2. Take the train from Brookhaven Station to Jacksontrain train
    3. Take the bus from Jackson to Memphis Bus Stationbus bus
    4. Take the bus from Tornado Bus Co - West Memphis to La Tropicana - Louisville, KYbus bus
    17h 17m
    $158–246

  4. Drive, train, bus

    1. Drive from Natchez to Brookhaven Stationcar car
    2. Take the train from Brookhaven Station to Carbondaletrain train
    3. Take the bus from Carbondale Intermodal Station to Clarksville Park & Ridebus bus
    4. Take the bus from Clarksville Park & Ride to Louisville Bus Stationbus bus
    20h 49m
    $193–402

  5. Drive to Baton Rouge Metropolitan Airport, fly

    1. Drive from Natchez to Baton-Rouge-Airport-BTRcar car
    2. Fly from Baton Rouge Metropolitan Airport (BTR) to Louisville International Airport (SDF)plane plane BTR - SDF
    7h 41m
    $136–675

  6. Taxi to Alexandria International Airport, fly

    1. Take the taxi from Natchez to Alexandria International Airport (AEX)taxi taxi
    2. Fly from Alexandria International Airport (AEX) to Louisville International Airport (SDF)plane plane AEX - SDF
    7h 23m
    $153–729

  7. Taxi to Monroe Regional Airport, fly

    1. Take the taxi from Natchez to Monroe Regional Airport (MLU)taxi taxi
    2. Fly from Monroe Regional Airport (MLU) to Louisville International Airport (SDF)plane plane MLU - SDF
    8h 27m
    $143–679

  8. Drive, train to Jackson/Vicksburg, fly

    1. Drive from Natchez to Brookhaven Stationcar car
    2. Take the train from Brookhaven Station to Jacksontrain train
    3. Fly from Jackson/Vicksburg (JAN) to Louisville International Airport (SDF)plane plane JAN - SDF
    8h 32m
    $157–705

  9. Drive, train, bus #2

    1. Drive from Natchez to Brookhaven Stationcar car
    2. Take the train from Brookhaven Station to Champaign-Urbanatrain train
    3. Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus
    21h 21m
    $222–497

  10. Drive, train, bus via Atlanta

    1. Drive from Natchez to Brookhaven Stationcar car
    2. Take the train from Brookhaven Station to Jacksontrain train
    3. Take the bus from Jackson to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Louisville Bus Stationbus bus
    21h 45m
    $146–302

Natchez (HEZ) to Louisville International Airport (SDF) flights

Calendar7Weekly Planes
Duration4h 25mAverage Duration
Ticket$155Cheapest Price
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Questions & Answers

Map of how to get from Natchez to Louisville.ExpandLaunch map view
  • Distance: 568.5 mi
  • Duration: 5h 53m

What companies run services between Natchez, MS, USA and Louisville, KY, USA?

United Airlines flies from Natchez (HEZ) to Louisville International Airport (SDF) once daily.

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