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How to get fromNatchez to St. Louisby plane, car, train, bus, or taxi

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There are 8 ways to get from Natchez to St. Louis by plane, car, train, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Natchez

    best
    1. Fly from Natchez (HEZ) to Lambert–St. Louis International Airport (STL)plane plane HEZ - STL
    5h 47m
    $161–686

  2. Drive, train, bus

    cheapest
    1. Drive from Natchez to Brookhaven Stationcar car
    2. Take the train from Brookhaven Station to Jacksontrain train
    3. Take the bus from Jackson to St Louis Bus Stationbus bus
    13h 30m
    $104–202

  3. Drive, train, bus via Carbondale

    1. Drive from Natchez to Brookhaven Stationcar car
    2. Take the train from Brookhaven Station to Carbondaletrain train
    3. Take the bus from Carbondale to St. Louisbus bus
    15h 14m
    $186–397

  4. Drive 572.1 mi

    1. Drive from Natchez to St. Louiscar car 572.1 mi
    10h 24m
    $105–151

  5. Taxi to Alexandria International Airport, fly

    1. Take the taxi from Natchez to Alexandria International Airport (AEX)taxi taxi
    2. Fly from Alexandria International Airport (AEX) to Lambert–St. Louis International Airport (STL)plane plane AEX - STL
    6h 57m
    $145–679

  6. Drive to Baton Rouge Metropolitan Airport, fly

    1. Drive from Natchez to Baton-Rouge-Airport-BTRcar car
    2. Fly from Baton Rouge Metropolitan Airport (BTR) to Lambert–St. Louis International Airport (STL)plane plane BTR - STL
    6h 44m
    $148–675

  7. Taxi to Monroe Regional Airport, fly

    1. Take the taxi from Natchez to Monroe Regional Airport (MLU)taxi taxi
    2. Fly from Monroe Regional Airport (MLU) to Lambert–St. Louis International Airport (STL)plane plane MLU - STL
    7h 13m
    $145–679

  8. Drive, train to Jackson/Vicksburg, fly

    1. Drive from Natchez to Brookhaven Stationcar car
    2. Take the train from Brookhaven Station to Jacksontrain train
    3. Fly from Jackson/Vicksburg (JAN) to Lambert–St. Louis International Airport (STL)plane plane JAN - STL
    7h 42m
    $167–655

Natchez (HEZ) to Lambert–St. Louis International Airport (STL) flights

Calendar12Weekly Planes
Duration6h 48mAverage Duration
Ticket$135Cheapest Price
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Questions & Answers

Map of how to get from Natchez to St. Louis.ExpandLaunch map view
  • Distance: 519.3 mi
  • Duration: 5h 47m

What companies run services between Natchez, MS, USA and St. Louis, MO, USA?

United Airlines flies from Natchez (HEZ) to Lambert–St. Louis International Airport (STL) twice daily.

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