There are 4 ways to get from Natick to Portsmouth by train, bus, car, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Natick Center to South Stationtrain Framingham/Worcester Line
- Take the bus from Boston to Portsmouth Bus Stopbus FlixBus N2615
2h 46m$11–26Drive 70.3 mi
- Drive from Natick to Portsmouthcar 70.3 mi
1h 33m$13–19Train, bus via Terminal A – LEX Drop Off
- Take the train from Natick Center to Back Baytrain Framingham/Worcester Line
- Take the bus from Boston to Portsmouthbus Cj00:40-Lgpm
3h 53m$27–45Bus
- Take the bus from Framingham to Bostonbus Greyhound US0270s
- Take the bus from Boston to Portsmouth Bus Stopbus FlixBus N2615
3h 58m$12–30
Natick to Portsmouth by train and bus
Questions & Answers
The cheapest way to get from Natick to Portsmouth is to drive which costs $12 - $19 and takes 1h 33m.
The fastest way to get from Natick to Portsmouth is to drive which takes 1h 33m and costs $12 - $19.
No, there is no direct bus from Natick to Portsmouth. However, there are services departing from Framingham and arriving at Portsmouth Bus Stop via Boston. The journey, including transfers, takes approximately 3h 58m.
The distance between Natick and Portsmouth is 75 miles. The road distance is 70.7 miles.
The best way to get from Natick to Portsmouth without a car is to train and bus which takes 2h 46m and costs $11 - $26.
It takes approximately 2h 46m to get from Natick to Portsmouth, including transfers.
Natick to Portsmouth bus services, operated by Greyhound USA, depart from Framingham station.
Natick to Portsmouth bus services, operated by Greyhound USA, arrive at Boston station.
Yes, the driving distance between Natick to Portsmouth is 71 miles. It takes approximately 1h 33m to drive from Natick to Portsmouth.
There are 378+ hotels available in Portsmouth.
What companies run services between Natick, MA, USA and Portsmouth, NH, USA?
You can take a train from Natick Center to Portsmouth Bus Stop via Framingham, Framingham, and Boston in around 3h 58m.
Train from Natick Center to South Station
- Ave. Duration
- 46 min
- Frequency
- Hourly
- Estimated price
- $3–9
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $3–9
Train from Natick Center to Back Bay
- Ave. Duration
- 40 min
- Frequency
- Hourly
- Estimated price
- $3–9
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $3–9
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Boston to Portsmouth Bus Stop
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $8–15
- Schedules at
- Flixbus USA
Bus from Boston to Portsmouth Bus Stop
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $8–15
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Boston to Portsmouth Bus Stop
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $8–17
- Website
- Greyhound
Bus from Framingham to Boston
- Ave. Duration
- 50 min
- Frequency
- Once daily
- Estimated price
- $3–7
- Website
- Greyhound
Bus from Boston to Portsmouth Bus Stop
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $8–17
- Website
- Greyhound
- Phone
- +1 603-430-1100
- Website
- C & J Travel
Bus from Boston to Portsmouth
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $15–27
- Website
- C & J Travel
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide












