Rome2Rio

How to get fromNebraska to Mayo Clinicby bus (Greyhound), car, plane, or bus

Find Transport to Mayo Clinic

See all options

There are 5 ways to get from Nebraska to Mayo Clinic by bus (Greyhound), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Omaha, NE to Des Moinesbus bus
    2. Take the bus from Des Moines to Saint Paul Union Depotbus bus
    3. Take the bus from St. Paul to Rochesterbus bus
    11h 24m
    $82–146
  2. Drive  339.3 mi

    cheapest
    1. Drive from Omaha to Mayo Cliniccar car 339.3 mi
    5h 42m
    $62–90
  3. Fly to Rochester

    1. Fly from Omaha (OMA) to Rochester (RST)plane plane OMA - RST
    7h 13m
    $62–441
  4. Bus via Sioux Falls

    1. Take the bus from Omaha to Sioux Fallsbus bus
    2. Take the bus from Sioux Falls to Minneapolis-St. Paulbus bus
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    15h 17m
    $178–233
  5. Fly to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Omaha (OMA) to Minneapolis–Saint Paul International Airport (MSP)plane plane OMA - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    5h 30m
    $603–1,003

Nebraska to Mayo Clinic by bus and foot

Calendar7Weekly Services
Duration11h 24mAverage Duration
Ticket$82Cheapest Price
See schedules

Questions & Answers

What companies run services between Nebraska, USA and Mayo Clinic, MN, USA?

You can take a bus from Omaha, NE to Mayo Clinic via Des Moines, St. Paul, and Rochester in around 11h 24m. Alternatively, American Airlines, Delta, and United Airlines fly from Omaha (OMA) to Rochester (RST) every 4 hours.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers