There are 5 ways to get from Nebraska to Mayo Clinic by plane, bus (Greyhound), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Rochester
best- Fly from Omaha (OMA) to Rochester (RST)plane OMA - RST
5h 42m$62–441Bus
- Take the bus from Omaha, NE to Des Moinesbus
- Take the bus from Des Moines to Minneapolis Bus Stationbus
- Take the bus from Minneapolis to Rochesterbus
11h 3m$87–144Drive 339.3 mi
- Drive from Omaha to Mayo Cliniccar 339.3 mi
5h 42m$62–90Fly to Minneapolis–Saint Paul International Airport, bus
- Fly from Omaha (OMA) to Minneapolis–Saint Paul International Airport (MSP)plane OMA - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
5h 44m$601–1,001Bus via Sioux Falls
- Take the bus from Omaha to Sioux Fallsbus
- Take the bus from Sioux Falls to Minneapolis-St. Paulbus
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
15h 17m$178–233
Nebraska to Mayo Clinic by bus and foot
Comparing Your Travel Options
The cheapest way to get from Nebraska to Mayo Clinic is to drive which costs $60 - $90 and takes 5h 42m.
The fastest way to get from Nebraska to Mayo Clinic is to drive which takes 5h 42m and costs $60 - $90.
No, there is no direct bus from Nebraska to Mayo Clinic. However, there are services departing from Omaha, NE and arriving at Rochester via Des Moines and Minneapolis. The journey, including transfers, takes approximately 11h 3m.
The distance between Nebraska and Mayo Clinic is 265 miles. The road distance is 341.3 miles.
The best way to get from Nebraska to Mayo Clinic without a car is to bus which takes 11h 3m and costs $85 - $150.
It takes approximately 5h 42m to get from Nebraska to Mayo Clinic, including transfers.
Nebraska to Mayo Clinic bus services, operated by Greyhound USA, depart from Omaha, NE station.
The best way to get from Nebraska to Mayo Clinic is to fly which takes 5h 42m and costs $60 - $450. Alternatively, you can bus, which costs $85 - $150 and takes 11h 3m.
Nebraska to Mayo Clinic bus services, operated by Greyhound USA, arrive at Des Moines station.
Yes, the driving distance between Nebraska to Mayo Clinic is 341 miles. It takes approximately 5h 42m to drive from Nebraska to Mayo Clinic.
What companies run services between Nebraska, USA and Mayo Clinic, MN, USA?
Delta, American Airlines, and United Airlines fly from Omaha (OMA) to Rochester (RST) every 4 hours. Alternatively, you can take a bus from Omaha, NE to Mayo Clinic via Des Moines, Minneapolis, and Rochester in around 11h 3m.
- Website
- delta.com
Flights from Omaha to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- $60–400
Flights from Omaha to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $70–470
- Website
- aa.com
Flights from Omaha to Rochester via Chicago O'Hare
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $85–480
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Omaha, NE to Des Moines
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $21–35
- Website
- Greyhound
Bus from Des Moines to Minneapolis Bus Station
- Ave. Duration
- 4h 25m
- Frequency
- Once daily
- Estimated price
- $35–65
- Website
- Greyhound
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Minneapolis to Rochester
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $30–45
- Book at
- Jefferson Lines
- Adult
- $30–45
Bus from Omaha to Sioux Falls
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from Sioux Falls to Minneapolis-St. Paul
- Ave. Duration
- 7h 20m
- Frequency
- Once daily
- Estimated price
- $75–110
- Book at
- Jefferson Lines
- Adult
- $75–110
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 45m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 45m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
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Booking & Getting There
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