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How to get fromNeu-Isenburg to Karlsruheby train, bus, or car

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There are 5 ways to get from Neu-Isenburg to Karlsruhe by train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Frankfurt to Karlsruhe Hauptbahnhoftrain train 12 / ...
    1h 59m
    €28–113

  2. Bus

    cheapest
    1. Take the bus from Frankfurt Airport to Karlsruhe central train stationbus bus FlixBus 108 / ...
    3h 5m
    €12–24

  3. Drive 130 km

    1. Drive from Neu-Isenburg to Karlsruhecar car 130 km
    1h 17m
    €19–27

  4. Bus, train

    1. Take the bus from Neu-Isenburg Isenburgzentrum West to Langenbus bus
    2. Take the train from Langen to Mannheim, Hauptbahnhoftrain train
    3. Take the train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain train 12 / ...
    2h 49m

  5. Bus, train via Gernsheim

    1. Take the bus from Neu-Isenburg Isenburgzentrum Süd to Mörfelden-Walldorf-Walldorf Bahnhofbus bus X18
    2. Take the train from Groß-Rohrheim, Bahnhof to Karlsruhe Hauptbahnhoftrain train S9
    3h 41m

Neu-Isenburg to Karlsruhe by tram and train

Calendar130Weekly Services
Duration1h 59mAverage Duration
Ticket€28Cheapest Price
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Questions & Answers

Map of how to get from Neu-Isenburg to Karlsruhe.ExpandLaunch map view
  • Distance: 144 km
  • Duration: 1h 59m

What companies run services between Neu-Isenburg, Germany and Karlsruhe, Germany?

Deutsche Bahn Intercity (DB IC) operates a train from Frankfurt to Karlsruhe Hauptbahnhof hourly. Tickets cost €25–110 and the journey takes 1h 9m. Österreichische Bundesbahnen also services this route twice a week. Alternatively, FlixBus operates a bus from Frankfurt Airport to Karlsruhe central train station hourly. Tickets cost €12–21 and the journey takes 2h 10m. BlaBlaCar Bus also services this route every 4 hours.

Train operators
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