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How to get fromNew Buffalo Station to Mayo Clinicby train, plane, bus (Amtrak, Greyhound, Flixbus), bus, car, or bus (Amtrak)

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There are 9 ways to get from New Buffalo Station to Mayo Clinic by train, plane, bus (Amtrak, Greyhound, Flixbus), bus, car, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Chicago O'Hare International Airport, fly to Rochester

    best
    1. Take the train from New Buffalo Station to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Rochester (RST)plane plane ORD - RST
    6h 24m
    $63–375

  2. Bus via Milwaukee

    1. Take the bus from New Buffalo Station to Chicago Union Stationbus bus
    2. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    3. Take the bus from Milwaukee to Rochesterbus bus
    10h 53m
    $106–158

  3. Train, bus

    1. Take the train from New Buffalo Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    3. Take the bus from St. Paul to Rochesterbus bus
    12h 45m
    $178–350

  4. Drive 415.5 mi

    1. Drive from New Buffalo Station to Mayo Cliniccar car 415.5 mi
    6h 59m
    $76–110

  5. Train to South Bend, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the train from 11th Street to South Bend Airporttrain train
    2. Fly from South Bend (SBN) to Minneapolis–Saint Paul International Airport (MSP)plane plane SBN - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    6h 39m
    $169–573

  6. Train to Chicago O'Hare International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the train from New Buffalo Station to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Minneapolis–Saint Paul International Airport (MSP)plane plane ORD - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 7m
    $294–547

  7. Train to Chicago Midway International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the train from New Buffalo Station to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Minneapolis–Saint Paul International Airport (MSP)plane plane MDW - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 57m
    $152–580

  8. Train, bus via Milwaukee

    1. Take the train from New Buffalo Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Milwaukeetrain train
    3. Take the bus from Milwaukee to Rochesterbus bus
    10h 58m
    $117–200

  9. Bus

    1. Take the bus from New Buffalo Station to Chicago Union Stationbus bus
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    11h 27m
    $98–162

New Buffalo Station to Mayo Clinic by bus and foot

Calendar2Weekly Services
Duration10h 53mAverage Duration
Ticket$106Cheapest Price
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Questions & Answers

Map of how to get from New Buffalo Station to Mayo Clinic.ExpandLaunch map view
  • Distance: 357 mi
  • Duration: 6h 24m

What companies run services between New Buffalo Station, MI, USA and Mayo Clinic, MN, USA?

You can take a bus from New Buffalo Station to Mayo Clinic via Chicago Union Station, Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 10h 53m.

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Bus operators

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