There are 8 ways to get from New Lenox to Mayo Clinic by train, plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Chicago O'Hare International Airport, fly to Rochester
best- Take the train from New Lenox to LaSalle Streettrain
- Fly from Chicago O'Hare International Airport (ORD) to Rochester (RST)plane ORD - RST
5h 33m$48–341Train, bus via Milwaukee
- Take the train from New Lenox to LaSalle Streettrain Ri
- Take the train from Chicago Union Station to Milwaukeetrain
- Take the bus from Milwaukee to Rochesterbus
10h 34m$105–169Train, bus
- Take the train from New Lenox to LaSalle Streettrain Ri
- Take the train from Chicago Union Station to St. Paul-Minneapolistrain
- Take the bus from St. Paul to Rochester, MNbus
12h 26m$166–319Drive 358.7 mi
- Drive from New Lenox to Mayo Cliniccar 358.7 mi
6h 7m$66–95Train to Chicago O'Hare International Airport, fly to Minneapolis–Saint Paul International Airport, bus
- Take the train from New Lenox to LaSalle Streettrain
- Fly from Chicago O'Hare International Airport (ORD) to Minneapolis–Saint Paul International Airport (MSP)plane ORD - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
7h 16m$279–513Train to Chicago Midway International Airport, fly to Minneapolis–Saint Paul International Airport, bus
- Take the train from New Lenox to LaSalle Streettrain
- Fly from Chicago Midway International Airport (MDW) to Minneapolis–Saint Paul International Airport (MSP)plane MDW - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
7h 15m$134–543Train, bus via Lake Delton
- Take the train from New Lenox to LaSalle Streettrain Ri
- Take the bus from Chicago Bus Station to Wisconsin Dellsbus
- Take the bus from Wisconsin Dells to Rochester, MNbus
11h 8m$83–134Train, bus #2
- Take the train from New Lenox to LaSalle Streettrain Ri
- Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus
- Take the bus from Madison to Rochesterbus
11h 23m$83–139
New Lenox to Mayo Clinic by train, foot, and bus
Questions & Answers
The cheapest way to get from New Lenox to Mayo Clinic is to drive which costs $65 - $95 and takes 6h 7m.
The fastest way to get from New Lenox to Mayo Clinic is to train and fly which takes 5h 33m and costs $45 - $350.
The distance between New Lenox and Mayo Clinic is 331 miles. The road distance is 360.8 miles.
The best way to get from New Lenox to Mayo Clinic without a car is to train and bus via Milwaukee which takes 10h 34m and costs $100 - $170.
It takes approximately 5h 33m to get from New Lenox to Mayo Clinic, including transfers.
Yes, the driving distance between New Lenox to Mayo Clinic is 361 miles. It takes approximately 6h 7m to drive from New Lenox to Mayo Clinic.
There are 75+ hotels available in Mayo Clinic.
What companies run services between New Lenox, IL, USA and Mayo Clinic, MN, USA?
There is no direct connection from New Lenox to Mayo Clinic. However, you can take the train to LaSalle Street, walk to LaSalle, take the subway to O'Hare, walk to Chicago O'Hare International Airport (ORD) airport, fly to Rochester (RST), walk to Rochester - Airport, take the shuttle to Rochester, then walk to Mayo Clinic. Alternatively, you can take a train from New Lenox to Mayo Clinic via LaSalle Street, Adams & S. Wacker, Union Station Transit Center, Chicago Union Station, Milwaukee, Milwaukee, and Rochester in around 10h 34m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $75–480
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Rochester
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $40–290
Flights from Chicago O'Hare International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $60–370
- Website
- delta.com
Flights from Chicago O'Hare International Airport to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- $50–320
Flights from Chicago O'Hare International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $60–370
Flights from Chicago Midway International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $75–480
- Website
- united.com
Flights from Chicago O'Hare International Airport to Rochester
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $40–290
Flights from Chicago O'Hare International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $60–370
- Website
- suncountry.com
Flights from Chicago O'Hare International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 41m
- When
- Sunday, Monday, and Thursday
- Estimated price
- $60–370
- Phone
- +1 312-696-3872
- Website
- metra.com
Train from New Lenox to LaSalle Street
- Ave. Duration
- 1h 2m
- Frequency
- Hourly
- Estimated price
- $5–7
- Website
- https://metra.com
- Adult
- $5–7
Train from New Lenox to LaSalle Street
- Ave. Duration
- 1h 2m
- Frequency
- Hourly
- Estimated price
- $5–7
- Website
- https://metra.com
- Adult
- $5–7
Train from New Lenox to LaSalle Street
- Ave. Duration
- 1h 2m
- Frequency
- Hourly
- Estimated price
- $5–7
- Website
- https://metra.com
- Adult
- $5–7
Train from New Lenox to LaSalle Street
- Ave. Duration
- 1h 2m
- Frequency
- Hourly
- Estimated price
- $5–7
- Website
- https://metra.com
- Adult
- $5–7
Train from New Lenox to LaSalle Street
- Ave. Duration
- 1h 2m
- Frequency
- Hourly
- Estimated price
- $5–7
- Website
- https://metra.com
- Adult
- $5–7
Train from New Lenox to LaSalle Street
- Ave. Duration
- 1h 2m
- Frequency
- Hourly
- Estimated price
- $5–7
- Website
- https://metra.com
- Adult
- $5–7
Train from New Lenox to LaSalle Street
- Ave. Duration
- 1h 2m
- Frequency
- Hourly
- Estimated price
- $5–7
- Website
- https://metra.com
- Adult
- $5–7
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $27–60
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to St. Paul-Minneapolis
- Ave. Duration
- 7h 31m
- Frequency
- 3 times a day
- Estimated price
- $130–270
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Milwaukee to Rochester
- Ave. Duration
- 5h 40m
- Frequency
- 3 times a day
- Estimated price
- $70–100
- Book at
- https://www.jeffersonlines.com
- Adult
- $70–100
Bus from St. Paul to Rochester, MN
- Ave. Duration
- 1h 30m
- Frequency
- 3 times a day
- Estimated price
- $28–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $28–40
Bus from Wisconsin Dells to Rochester, MN
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $45–65
- Book at
- https://www.jeffersonlines.com
- Adult
- $45–65
Bus from Madison to Rochester
- Ave. Duration
- 4h 20m
- Frequency
- 3 times a day
- Estimated price
- $50–75
- Book at
- https://www.jeffersonlines.com
- Adult
- $50–75
- Phone
- + 1 507-280-9270
- Website
- groometransportation.com
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- https://groometransportation.com/minneapolis-st-paul-airport/rochester
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- https://groometransportation.com/minneapolis-st-paul-airport/rochester
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Chicago Bus Station to Wisconsin Dells
- Ave. Duration
- 3h 50m
- Frequency
- 3 times a day
- Estimated price
- $30–60
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Chicago Bus Station to Wisconsin Dells
- Ave. Duration
- 4h 55m
- Frequency
- Once daily
- Estimated price
- $30–60
- Schedules at
- flixbus.com
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- coachusa.com
Bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 3h 50m
- Frequency
- Hourly
- Estimated price
- $25–55
- Schedules at
- coachusa.com
- Adult
- $25–55
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide












