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How to get fromNew Madrid to St. Louisby taxi, bus, car, or train

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There are 3 ways to get from New Madrid to St. Louis by taxi, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, bus (Greyhound)

    best
    1. Take the taxi from New Madrid to Cape Girardeautaxi taxi
    2. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus Greyhound US1173
    2h 43m
    $161–198

  2. Drive  163.7 mi

    cheapest
    1. Drive from New Madrid to St. Louiscar car 163.7 mi
    2h 43m
    $30–44

  3. Drive, train (Amtrak)

    1. Drive from New Madrid to Poplar Bluff Stationcar car
    2. Take the train from Poplar Bluff Station to St. Louistrain train Texas Eagle
    6h 4m
    $51–110

Comparing Your Travel Options

Map of how to get from New Madrid to St. Louis.ExpandLaunch map view
  • Distance: 164.8 mi
  • Duration: 2h 43m

What companies run services between New Madrid, MO, USA and St. Louis, MO, USA?

There is no direct connection from New Madrid to St. Louis. However, you can take the taxi to Cape Girardeau then take the bus to St Louis Bus Station. Alternatively, you can take a vehicle from New Madrid to St. Louis via Poplar Bluff Station in around 6h 4m.

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Need to know: Greyhound

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