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How to get fromNew Orleans to Columbiaby plane, bus (Greyhound), train, bus, or car

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There are 6 ways to get from New Orleans to Columbia by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louis Armstrong New Orleans International Airport to Columbia Regional Airport

    best
    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Columbia Regional Airport (COU)plane plane MSY - COU
    6h 17m
    $162–667

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from New Orleans Bus Station to St Louis Bus Stationbus bus Greyhound US1173
    2. Take the bus from St Louis Bus Station to Columbiabus bus Greyhound US0175s
    18h 40m
    $126–238

  3. Train, bus

    1. Take the train from New Orleans Union Passenger Terminal to Carbondaletrain train
    2. Take the bus from Carbondale to St. Louisbus bus
    3. Take the bus from St Louis Bus Station to Columbiabus bus
    20h 28m
    $224–483

  4. Drive 755.5 mi

    1. Drive from New Orleans to Columbiacar car 755.5 mi
    13h 12m
    $138–200

  5. Train to Gulfport-Biloxi Regional Airport, fly to Columbia Regional Airport

    1. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Columbia Regional Airport (COU)plane plane GPT - COU
    7h 58m
    $195–726

  6. Fly Louis Armstrong New Orleans International Airport to Lambert–St. Louis International Airport, bus

    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Lambert–St. Louis International Airport (STL)plane plane MSY - STL
    2. Take the bus from St Louis Bus Station to Columbiabus bus
    8h 11m
    $426–945

New Orleans to Columbia by bus (Greyhound)

Calendar7Weekly Buses
Duration18h 40mAverage Duration
Ticket$126Cheapest Price
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Questions & Answers

Map of how to get from New Orleans to Columbia.ExpandLaunch map view
  • Distance: 645.8 mi
  • Duration: 6h 17m

What companies run services between New Orleans, LA, USA and Columbia, MO, USA?

American Airlines, United Airlines, and Frontier Airlines fly from Louis Armstrong New Orleans International Airport (MSY) to Columbia Regional Airport (COU) every 4 hours. Alternatively, you can take a bus from New Orleans Bus Station to Columbia via St Louis Bus Station in around 18h 40m.

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