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How to get fromNew Orleans to Des Moinesby plane, bus (Greyhound), train, bus, or car

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There are 6 ways to get from New Orleans to Des Moines by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Louis Armstrong New Orleans International Airport

    best
    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Des Moines (DSM)plane plane MSY - DSM
    6h 24m
    $229–973

  2. Bus

    cheapest
    1. Take the bus from New Orleans Bus Station to St Louis Bus Stationbus bus Greyhound US1173
    2. Take the bus from St Louis Bus Station to Des Moinesbus bus Greyhound US0153S
    24h 10m
    $177–341

  3. Train, bus

    1. Take the train from New Orleans Union Passenger Terminal to Champaign-Urbanatrain train City of New Orleans
    2. Take the bus from Champaign Intermodal Trans Ctr to Des Moinesbus bus Greyhound US0157S
    25h 25m
    $313–636

  4. Drive 991.2 mi

    1. Drive from New Orleans to Des Moinescar car 991.2 mi
    17h 17m
    $181–262

  5. Train to Gulfport-Biloxi Regional Airport, fly

    1. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Des Moines (DSM)plane plane GPT - DSM
    7h
    $264–1,033

  6. Train, bus via Des Moines

    1. Take the train from New Orleans Union Passenger Terminal to Champaign-Urbanatrain train City of New Orleans
    2. Take the bus from Champaign to Des Moinesbus bus Btw 1401
    27h 35m

New Orleans to Des Moines by bus

Calendar7Weekly Buses
Duration24h 10mAverage Duration
Ticket$177Cheapest Price
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Questions & Answers

Map of how to get from New Orleans to Des Moines.ExpandLaunch map view
  • Distance: 838.9 mi
  • Duration: 6h 24m

What companies run services between New Orleans, LA, USA and Des Moines, IA, USA?

Southwest Airlines, Delta, and two other airlines fly from Louis Armstrong New Orleans International Airport (MSY) to Des Moines (DSM) every 3 hours. Alternatively, you can take a bus from New Orleans Bus Station to Des Moines via St Louis Bus Station in around 24h 10m.

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Need to know: Greyhound

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