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How to get fromNew Orleans to Florida Keysby plane, bus (Greyhound, Flixbus), car, shuttle, train, or bus

Find Transport to Florida Keys

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There are 6 ways to get from New Orleans to Florida Keys by plane, bus (Greyhound, Flixbus), car, shuttle, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Key West International Airport

    best
    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Key West International Airport (EYW)plane plane MSY - EYW
    8h 46m
    $154–506

  2. Bus

    1. Take the bus from New Orleans Bus Station to Biloxi Transit Centerbus bus
    2. Take the bus from Biloxi to Miamibus bus
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    25h 59m
    $182–259

  3. Drive  985.6 mi

    1. Drive from New Orleans to Florida Keyscar car 985.6 mi
    17h 25m
    $175–252

  4. Fly to Miami International Airport, shuttle

    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Miami International Airport (MIA)plane plane MSY - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    9h 9m
    $754–1,286

  5. Fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane MSY - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    9h 33m
    $274–806

  6. Train, bus, shuttle

    1. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    2. Take the bus from Gulfport to Miamibus bus
    3. Take a shuttle bus from Bayside Marketplace to Plaza Hotelshuttle bus
    26h 34m
    $234–306

Louis Armstrong New Orleans International Airport (MSY) to Key West International Airport (EYW) flights

Calendar51Weekly Planes
Duration5h 29mAverage Duration
Ticket$79Cheapest Price
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Comparing Your Travel Options

Map of how to get from New Orleans to Florida Keys.ExpandLaunch map view
  • Distance: 676.1 mi
  • Duration: 8h 46m

What companies run services between New Orleans, LA, USA and Florida Keys, FL, USA?

American Airlines, Delta, and United Airlines fly from Louis Armstrong New Orleans International Airport (MSY) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from New Orleans Bus Station to Florida Keys via Biloxi Transit Center, Biloxi, Miami, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 25h 59m.

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