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How to get fromNew Orleans to Great Smoky Mountainsby plane, car, bus, or train

Find Transport to Great Smoky Mountains

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There are 8 ways to get from New Orleans to Great Smoky Mountains by plane, car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louis Armstrong New Orleans International Airport to Mcghee Tyson Airport, drive

    best
    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Mcghee Tyson Airport (TYS)plane plane MSY - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    6h 54m
    $172–918

  2. Fly Louis Armstrong New Orleans International Airport to Asheville Regional Airport, drive

    cheapest
    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Asheville Regional Airport (AVL)plane plane MSY - AVL
    2. Drive from Asheville-Airport-AVL to Great Smoky Mountainscar car
    7h 30m
    $96–494

  3. Bus, drive (Greyhound)

    1. Take the bus from New Orleans Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus bus
    3. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    4. Drive from Asheville, NC to Great Smoky Mountainscar car
    21h 23m
    $150–294

  4. Train, bus, drive

    1. Take the train from New Orleans Union Passenger Terminal to Greensborotrain train
    2. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    3. Drive from Asheville, NC to Great Smoky Mountainscar car
    27h 30m
    $311–640

  5. Drive 643.7 mi

    1. Drive from New Orleans to Great Smoky Mountainscar car 643.7 mi
    11h 44m
    $118–170

  6. Train to Gulfport-Biloxi Regional Airport, fly to Mcghee Tyson Airport, drive

    1. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Mcghee Tyson Airport (TYS)plane plane GPT - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    7h 39m
    $186–928

  7. Fly Louis Armstrong New Orleans International Airport to Hartsfield-Jackson Atlanta International Airport, drive

    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane MSY - ATL
    2. Drive from Atlanta-Airport-ATL to Great Smoky Mountainscar car
    7h 17m
    $147–657

  8. Fly Louis Armstrong New Orleans International Airport to Nashville, drive

    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Nashville (BNA)plane plane MSY - BNA
    2. Drive from Nashville-Airport-BNA to Great Smoky Mountainscar car
    7h 51m
    $842–1,017

Louis Armstrong New Orleans International Airport (MSY) to Mcghee Tyson Airport (TYS) flights

Calendar65Weekly Planes
Duration4hAverage Duration
Ticket$162Cheapest Price
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Questions & Answers

Map of how to get from New Orleans to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 613.4 mi
  • Duration: 6h 54m

What companies run services between New Orleans, LA, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from New Orleans to Great Smoky Mountains. However, you can take the bus to Kenner Terminal Parking Garage, walk to Louis Armstrong New Orleans International Airport (MSY) airport, fly to Mcghee Tyson Airport (TYS), then drive to Great Smoky Mountains. Alternatively, you can take a bus from New Orleans Bus Station to Great Smoky Mountains via Atlanta Bus Station, Winston Salem(Trans Center), and Asheville, NC in around 21h 23m.

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