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How to get fromNew Orleans to Lake Cityby train, bus, car, plane, or bus (Greyhound, Flixbus)

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There are 8 ways to get from New Orleans to Lake City by train, bus, car, plane, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train Amtrak Mardi Gras Service / ...
    2. Take the bus from Gulfport to Lake Citybus bus Houston
    9h 6m
    $116–166

  2. Bus

    cheapest
    1. Take the bus from New Orleans Bus Station to Mobile Bus Stationbus bus Greyhound US0602
    2. Take the bus from Mobile Bus Station to Lake City Bus Stationbus bus Greyhound US0760S
    13h
    $76–150

  3. Drive 487.5 mi

    1. Drive from New Orleans to Lake Citycar car 487.5 mi
    7h 54m
    $89–129

  4. Fly to Jacksonville, bus

    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Jacksonville (JAX)plane plane MSY - JAX
    2. Take the bus from Jacksonville to Lake City Bus Stationbus bus
    6h 50m
    $452–973

  5. Train, bus via Mobile

    1. Take the train from New Orleans Union Passenger Terminal to Mobile Amtrak Statrain train Amtrak Mardi Gras Service / ...
    2. Take the bus from Mobile Bus Station to Lake City Bus Stationbus bus Greyhound US0760S
    15h 3m
    $85–200

  6. Fly to Orlando, bus

    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Orlando (MCO)plane plane MSY - MCO
    2. Take the bus from Orlando Bus Station to Lake City Bus Stationbus bus
    9h 54m
    $119–521

  7. Fly to Gainesville Regional Airport, bus

    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Gainesville Regional Airport (GNV)plane plane MSY - GNV
    2. Take the bus from Gainesville Bus Stop to Lake City Bus Stationbus bus
    10h 26m
    $107–508

  8. Fly to Valdosta, bus

    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Valdosta (VLD)plane plane MSY - VLD
    2. Take the bus from Valdosta to Gainesville Bus Stopbus bus
    3. Take the bus from Gainesville Bus Stop to Lake City Bus Stationbus bus
    10h 52m
    $121–530

New Orleans to Lake City by bus

Calendar7Weekly Buses
Duration13hAverage Duration
Ticket$76Cheapest Price
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Questions & Answers

Map of how to get from New Orleans to Lake City.ExpandLaunch map view
  • Distance: 507.4 mi
  • Duration: 9h 6m

What companies run services between New Orleans, LA, USA and Lake City, FL, USA?

You can take a bus from New Orleans Bus Station to Lake City Bus Station via Mobile Bus Station in around 13h.

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Train operators
Bus operators

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