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How to get fromNew Orleans to Louisville, KYby plane, bus (Greyhound), car, train, or bus

Find Transport to Louisville, KY

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There are 7 ways to get from New Orleans to Louisville, KY by plane, bus (Greyhound), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louis Armstrong New Orleans International Airport to Louisville International Airport

    best
    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Louisville International Airport (SDF)plane plane MSY - SDF
    5h 20m
    $223–705

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from New Orleans Bus Station to Montgomery Intermodal Centerbus bus Greyhound US0602
    2. Take the bus from Montgomery Intermodal Center to Louisville Bus Stationbus bus Greyhound US0112
    18h 5m
    $122–239

  3. Drive 705.1 mi

    1. Drive from New Orleans to Louisville, KYcar car 705.1 mi
    11h 27m
    $129–186

  4. Fly Louis Armstrong New Orleans International Airport to Blue Grass Airport, drive

    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Blue Grass Airport (LEX)plane plane MSY - LEX
    2. Drive from Lexington-Airport-LEX to Louisville, KYcar car
    6h 43m
    $215–1,122

  5. Train to Gulfport-Biloxi Regional Airport, fly to Louisville International Airport

    1. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Louisville International Airport (SDF)plane plane GPT - SDF
    8h 16m
    $167–765

  6. Fly Louis Armstrong New Orleans International Airport to Nashville, bus

    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Nashville (BNA)plane plane MSY - BNA
    2. Take the bus from Nashville Bus Station to Louisville Bus Stationbus bus
    7h 43m
    $580–1,054

  7. Fly Louis Armstrong New Orleans International Airport to Covington, bus

    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Covington (CVG)plane plane MSY - CVG
    2. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus
    7h 35m
    $183–749

New Orleans to Louisville, KY by bus (Greyhound)

Calendar14Weekly Buses
Duration18h 5mAverage Duration
Ticket$122Cheapest Price
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Questions & Answers

Map of how to get from New Orleans to Louisville, KY.ExpandLaunch map view
  • Distance: 643.2 mi
  • Duration: 5h 20m

What companies run services between New Orleans, LA, USA and Louisville, KY, USA?

Breeze Airways, Southwest Airlines, and two other airlines fly from Louis Armstrong New Orleans International Airport (MSY) to Louisville International Airport (SDF) 5 times a day. Alternatively, you can take a bus from New Orleans Bus Station to Louisville Bus Station via Montgomery Intermodal Center in around 18h 5m.

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