There are 6 ways to get from New Orleans to Poplar Bluff by bus, car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, drive (Greyhound)
best- Take the bus from New Orleans Bus Station to Cape Girardeaubus Greyhound US1173
- Drive from Cape Girardeau to Poplar Bluffcar
14h 15m$120–177Drive 534.5 mi
cheapest- Drive from New Orleans to Poplar Bluffcar 534.5 mi
9h 12m$98–141Fly to Lambert–St. Louis International Airport, train
- Fly from Louis Armstrong New Orleans International Airport (MSY) to Lambert–St. Louis International Airport (STL)plane MSY - STL
- Take the train from St. Louis to Poplar Bluff Stationtrain
8h 58m$565–995Fly to Jonesboro Municipal Airport, drive
- Fly from Louis Armstrong New Orleans International Airport (MSY) to Jonesboro Municipal Airport (JBR)plane MSY - JBR
- Drive from Jonesboro Municipal Airport (JBR) to Poplar Bluffcar
8h 3m$111–573Fly to Cape Girardeau Municipal Airport, drive
- Fly from Louis Armstrong New Orleans International Airport (MSY) to Cape Girardeau Municipal Airport (CGI)plane MSY - CGI
- Drive from Cape Girardeau Municipal Airport (CGI) to Poplar Bluffcar
7h 51m$144–671Fly to Mc Kellar-Sipes Regional Airport, drive
- Fly from Louis Armstrong New Orleans International Airport (MSY) to Mc Kellar-Sipes Regional Airport (MKL)plane MSY - MKL
- Drive from Mc Kellar-Sipes Regional Airport (MKL) to Poplar Bluffcar
8h 58m$121–592
Louis Armstrong New Orleans International Airport (MSY) to Lambert–St. Louis International Airport (STL) flights
Comparing Your Travel Options
The cheapest way to get from New Orleans to Poplar Bluff is to drive which costs $95 - $150 and takes 9h 12m.
The fastest way to get from New Orleans to Poplar Bluff is to fly and drive which takes 7h 51m and costs $140 - $700.
The distance between New Orleans and Poplar Bluff is 668 miles. The road distance is 537.6 miles.
It takes approximately 14h 15m to get from New Orleans to Poplar Bluff, including transfers.
Yes, the driving distance between New Orleans to Poplar Bluff is 538 miles. It takes approximately 9h 12m to drive from New Orleans to Poplar Bluff.
There are 10+ hotels available in Poplar Bluff.
What companies run services between New Orleans, LA, USA and Poplar Bluff, MO, USA?
There is no direct connection from New Orleans to Poplar Bluff. However, you can take the bus to Cape Girardeau then drive to Poplar Bluff. Alternatively, you can drive from New Orleans to Poplar Bluff in around 9h 12m.
- Website
- southwest.com
Flights from Louis Armstrong New Orleans International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- $120–700
Flights from Louis Armstrong New Orleans International Airport to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 3h 58m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $130–750
Flights from Louis Armstrong New Orleans International Airport to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 4h 5m
- When
- Monday, Thursday, and Friday
- Estimated price
- $150–800
Flights from Louis Armstrong New Orleans International Airport to Lambert–St. Louis International Airport via Dallas
- Ave. Duration
- 4h 10m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $160–850
Flights from Louis Armstrong New Orleans International Airport to Lambert–St. Louis International Airport via Houston Hobby Apt
- Ave. Duration
- 4h 10m
- When
- Tuesday, Wednesday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $160–850
- Website
- iflysouthern.com
Flights from Louis Armstrong New Orleans International Airport to Jonesboro Municipal Airport via Nashville
- Ave. Duration
- 4h 45m
- When
- Saturday, Monday, Thursday, Friday, and Wednesday
- Estimated price
- $95–550
Flights from Louis Armstrong New Orleans International Airport to Jonesboro Municipal Airport via Lambert–St. Louis International Airport
- Ave. Duration
- 8h 1m
- When
- Monday, Thursday, and Friday
- Estimated price
- $100–600
Flights from Louis Armstrong New Orleans International Airport to Jonesboro Municipal Airport via Houston Hobby Apt, Lambert–St. Louis International Airport
- Ave. Duration
- 6h 46m
- When
- Tuesday and Wednesday
- Estimated price
- $130–650
Flights from Louis Armstrong New Orleans International Airport to Jonesboro Municipal Airport via Kansas City, Lambert–St. Louis International Airport
- Ave. Duration
- 8h 11m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $130–650
Flights from Louis Armstrong New Orleans International Airport to Jonesboro Municipal Airport via Dallas, Lambert–St. Louis International Airport
- Ave. Duration
- 8h 36m
- When
- Friday
- Estimated price
- $130–650
Flights from Louis Armstrong New Orleans International Airport to Jonesboro Municipal Airport via Atlanta, Nashville
- Ave. Duration
- 9h 29m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $110–600
- Website
- contouraviation.com
Flights from Louis Armstrong New Orleans International Airport to Cape Girardeau Municipal Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 36m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $320–1,200
Flights from Louis Armstrong New Orleans International Airport to Cape Girardeau Municipal Airport via Chicago O'Hare
- Ave. Duration
- 5h 50m
- When
- Every day
- Estimated price
- $130–650
Flights from Louis Armstrong New Orleans International Airport to Cape Girardeau Municipal Airport via Houston, Dallas/Ft.Worth
- Ave. Duration
- 8h
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $340–1,300
- Website
- keylimeair.com
Flights from Louis Armstrong New Orleans International Airport to Mc Kellar-Sipes Regional Airport via Atlanta
- Ave. Duration
- 4h 35m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $95–550
Flights from Louis Armstrong New Orleans International Airport to Mc Kellar-Sipes Regional Airport via Chicago O'Hare
- Ave. Duration
- 7h 13m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $140–700
- Website
- delta.com
Flights from Louis Armstrong New Orleans International Airport to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 4h 10m
- When
- Friday
- Estimated price
- $150–800
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from St. Louis to Poplar Bluff Station
- Ave. Duration
- 3h 47m
- Frequency
- Once daily
- Estimated price
- $90–140
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from New Orleans Bus Station to Cape Girardeau
- Ave. Duration
- 12h 40m
- Frequency
- Once daily
- Estimated price
- $100–160
- Website
- Greyhound
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