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How to get fromNew Orleans to Port Isabelby plane, bus (Flixbus, Greyhound), train, bus, car, bus (Greyhound), or bus (Flixbus)

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There are 10 ways to get from New Orleans to Port Isabel by plane, bus (Flixbus, Greyhound), train, bus, car, bus (Greyhound), or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louis Armstrong New Orleans International Airport to Brownsville-South Padre Island International Airport

    best
    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Brownsville-South Padre Island International Airport (BRO)plane plane MSY - BRO
    7h 6m
    $114–654

  2. Bus via Victoria

    1. Take the bus from New Orleans Bus Station to Downtown Houstonbus bus
    2. Take the bus from Houston Bus Station to Victoriabus bus
    3. Take the bus from Victoria to Brownsville Bus Stationbus bus
    16h 15m
    $170–239

  3. Train, bus via Houston

    1. Take the train from New Orleans Union Passenger Terminal to Houstontrain train Sunset Limited
    2. Take the bus from Houston Bus Station to La Plaza at Brownsvillebus bus FlixBus US1126 / ...
    20h 39m
    $187–372

  4. Drive 710.3 mi

    1. Drive from New Orleans to Port Isabelcar car 710.3 mi
    13h 2m
    $130–188

  5. Train to Gulfport-Biloxi Regional Airport, fly to Brownsville-South Padre Island International Airport

    1. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    2. Fly from Gulfport-Biloxi Regional Airport (GPT) to Brownsville-South Padre Island International Airport (BRO)plane plane GPT - BRO
    7h 55m
    $159–714

  6. Fly Louis Armstrong New Orleans International Airport to Mcallen Miller International Airport, bus

    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Mcallen Miller International Airport (MFE)plane plane MSY - MFE
    2. Take the bus from McAllen Central Station to Brownsvillebus bus
    9h 39m
    $169–716

  7. Fly Louis Armstrong New Orleans International Airport to Rio Grande Valley International Airport, bus

    1. Fly from Louis Armstrong New Orleans International Airport (MSY) to Rio Grande Valley International Airport (HRL)plane plane MSY - HRL
    2. Take the bus from Harlingen Bus Station to Brownsvillebus bus
    9h 33m
    $126–506

  8. Bus

    1. Take the bus from New Orleans Bus Station to Houston Bus Stationbus bus Greyhound US0602
    2. Take the bus from Houston - Harrisburg Blvd to Brownsville Bus Stationbus bus Houston
    16h 55m
    $162–214

  9. Bus #2

    1. Take the bus from New Orleans Bus Station to Downtown Houstonbus bus FlixBus 2211 / ...
    2. Take the bus from Houston to Matamorosbus bus
    23h 33m
    $160–202

  10. Train, bus

    1. Take the train from New Orleans Union Passenger Terminal to San Antonio Stationtrain train Sunset Limited
    2. Take the bus from San Antonio to Brownsvillebus bus Dallas
    24h 7m
    $261–469

Louis Armstrong New Orleans International Airport (MSY) to Brownsville-South Padre Island International Airport (BRO) flights

Calendar54Weekly Planes
Duration4h 35mAverage Duration
Ticket$116Cheapest Price
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Questions & Answers

Map of how to get from New Orleans to Port Isabel.ExpandLaunch map view
  • Distance: 552.5 mi
  • Duration: 7h 6m

What companies run services between New Orleans, LA, USA and Port Isabel, TX, USA?

United Airlines and American Airlines fly from Louis Armstrong New Orleans International Airport (MSY) to Brownsville-South Padre Island International Airport (BRO) every 4 hours. Alternatively, you can take a bus from New Orleans Bus Station to Las Palmas Port Isabel via Downtown Houston, Houston Bus Station, Victoria, and La Plaza at Brownsville in around 16h 15m.

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